957828-80-7

Basic information

• Product Name: [5-(4-chlorophenyl)-3-(2-nitrophenyl)-4,5-dihydroisoxazol-4-yl](p-tolyl)methanone
• Synonyms: [5-(4-chlorophenyl)-3-(2-nitrophenyl)-4,5-dihydroisoxazol-4-yl](p-tolyl)methanone
• CAS NO: 957828-80-7
• Molecular Weight: 420.852
• Mol File: 957828-80-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [5-(4-chlorophenyl)-3-(2-nitrophenyl)-4,5-dihydroisoxazol-4-yl](p-tolyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [5-(4-chlorophenyl)-3-(2-nitrophenyl)-4,5-dihydroisoxazol-4-yl](p-tolyl)methanone(957828-80-7)
• EPA Substance Registry System: [5-(4-chlorophenyl)-3-(2-nitrophenyl)-4,5-dihydroisoxazol-4-yl](p-tolyl)methanone(957828-80-7)

Safety Data

• Hazardous Substances Data: 957828-80-7(Hazardous Substances Data)

Upstream product

• 35447-75-7 N-hydroxy-2-nitrobenzimidoyl chloride 
• 37620-37-4 (E)-4-chloro-4'-methylchalcone 

Relevant articles and documents

A general approach to the synthesis of substituted isoxazolo[4,3-c] quinolines via chalcones

A general and practical approach to the synthesis of substituted isoxazolo[4,3-c]quinolines from the substituted isoxazolines obtained by 1,3-dipolar cycloadditions between 2-nitrobenzonitrile oxide and chalcones is described. SnCl2·2H2O-mediated reduction of the nitro group, followed by intramolecular cyclization involving the amino and the keto groups in these substrates, furnished mixtures of isoxazolo[4,3-c] quinolines and 3,5-dihydroisoxazolo[4,3-c]-quinolines. In contrast, the reduction of these substrates with Fe/AcOH unexpectedly yielded 3-benzoylquinolin-4-yl-amine derivatives. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.