958299-80-4

Basic information

• Product Name: methyl (R)-5-(4-methylphenyl)hexanoate
• Synonyms: methyl (R)-5-(4-methylphenyl)hexanoate
• CAS NO: 958299-80-4
• Molecular Weight: 220.312
• Mol File: 958299-80-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (R)-5-(4-methylphenyl)hexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (R)-5-(4-methylphenyl)hexanoate(958299-80-4)
• EPA Substance Registry System: methyl (R)-5-(4-methylphenyl)hexanoate(958299-80-4)

Safety Data

• Hazardous Substances Data: 958299-80-4(Hazardous Substances Data)

Upstream product

• 122-00-9 para-methylacetophenone 
• 594-27-4 tetramethylstannane 

Downstream Products

• 4548-25-8 L-α-Curcumen 
• 4176-17-4 (R)-(-)-α-curcumene 

Relevant articles and documents

Stereospecific Hydrogenolysis of Lactones: Application to the Total Syntheses of (R)-ar-Himachalene and (R)-Curcumene

A straightforward strategy for the syntheses of curcumene and ar-himachalene is reported. Synthetic highlights include a catalytic and asymmetric vinylogous Mukaiyama reaction and a stereospecific hydrogenolysis of a tertiary benzylic center using Pd/C or Ni/Raney catalysts. Notably, using Ni/Raney, the stereoselectivity outcome (inversion vs retention) of the hydrogenolysis depends on the tertiary benzylic alcohol substitution.