959578-03-1

Basic information

• Product Name: 3,4-DICHLOROPICOLINIC ACID
• Synonyms: 3,4-DICHLOROPICOLINIC ACID;3,4-Dichloro-2-pyridinecarboxylic acid
• CAS NO: 959578-03-1
• Molecular Formula: C₆H₃Cl₂NO₂
• Molecular Weight: 192.001
• Mol File: 959578-03-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 317℃
• Flash Point: 145℃
• Appearance: /
• Density: 1.612
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.95±0.25(Predicted)
• CAS DataBase Reference: 3,4-DICHLOROPICOLINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DICHLOROPICOLINIC ACID(959578-03-1)
• EPA Substance Registry System: 3,4-DICHLOROPICOLINIC ACID(959578-03-1)

Safety Data

• Hazardous Substances Data: 959578-03-1(Hazardous Substances Data)

Usage

General Description

3,4-Dichloropicolinic acid is a chemical compound that is also known as 3,4-dichloropyridine-2-carboxylic acid. It is a white crystalline solid that is soluble in water and organic solvents. 3,4-Dichloropicolinic acid is commonly used as an intermediate in the synthesis of other chemicals such as herbicides and pesticides. It is also used as a building block in the pharmaceutical industry for the synthesis of pharmaceutical drugs. Additionally, 3,4-Dichloropicolinic acid has been studied for its potential use as a corrosion inhibitor for steel and as a reactant in the preparation of ruthenium complexes for catalytic applications. Overall, 3,4-Dichloropicolinic acid has a variety of applications in the chemical, pharmaceutical, and industrial sectors.

InChI:InChI=1S/C6H3Cl2NO2/c7-3-1-2-9-5(4(3)8)6(10)11/h1-2H,(H,10,11)

Upstream product

• 1211517-04-2 3,4-dichloropicolinaldehyde 
• 55934-00-4 3,4-dichloropyridine 
• 124-38-9 carbon dioxide 
• 626-60-8 3-Chloropyridine 

Downstream Products

• 1025720-99-3 3,4-dichloropyridine-2-carboxamide 
• 1203499-43-7 tert-butyl (3,4-dichloropyridin-2-yl)carbamate 
• 1025720-94-8 BMS-777607 
• 1025721-01-0 4-(4-amino-2-fluorophenoxy)-3-chloropyridine-2-carboxamide 

Relevant articles and documents

PHOSPHONATE CONJUGATES AND USES THEREOF

Phosphonate conjugates, preferably, bisphosphonate conjugates; methods of inhibiting Ron receptor tyrosine kinase and methods of treatment of bone destruction due to cancer or other conditions utilizing the provided phosphonate conjugates.

Electrophilicity and nucleophilicity of commonly used aldehydes

The present approach for determining the electrophilicity (E) and nucleophilicity (N) of aldehydes includes a kinetic study of KMNO4 oxidation and NaBH4 reduction of aldehydes. A transition state analysis of the KMNO4 promoted aldehyde oxidation reaction has been performed, which shows a very good correlation with experimental results. The validity of the experimental method has been tested using the experimental activation parameters of the two reactions. The utility of the present approach is further demonstrated by the theoretical versus experimental relationship, which provides easy access to E and N values for various aldehydes and offers an at-a-glance assessment of the chemical reactivity of aldehydes in various reactions. the Partner Organisations 2014.

PYRIDINONE COMPOUNDS

The invention is directed to pyridinone compounds useful for modulating Met kinase, having the following structure: and is further directed to pharmaceutical compositions comprising the compound; and methods for treating proliferative diseases, such as ca