960117-58-2Relevant articles and documents
Pd-Catalyzed Desulfonative Cross-Coupling of Benzylic Sulfone Derivatives with 1,3-Oxazoles
Yim, Jacky C.-H.,Nambo, Masakazu,Crudden, Cathleen M.
, p. 3715 - 3718 (2017)
The Pd-catalyzed desulfonative cross-coupling reaction of benzylic sulfone derivatives with 1,3-oxazoles via a deprotonative pathway has been developed. Broad substrate scope for both sulfone and 1,3-oxazole partners is observed, affording a variety of 1,3-oxazole-containing triarylmethanes. Sulfone partners that are primary benzylic, secondary benzylic, and benzhydryl are all effective. Using this method, the straightforward synthesis of multiply arylated structures has been demonstrated.
Sequential copper-catalyzed vinylation/ cyclization: An efficient synthesis of functionalized oxazoles
Martin, Ruben,Cuenca, Ana,Buchwald, Stephen L.
, p. 5521 - 5524 (2008/09/17)
A modular and practical synthesis of highly substituted oxazoles has been developed. The transformation consists of a sequential copper-catalyzed amidation of vinyl halides followed by cyclization promoted by iodine. A wide variety of functionalized oxazo
