960529-90-2

Basic information

• Product Name: benzyl (2S,3aS,7aS)-N-(tert-butoxycarbonyl)octahydroindole-2-carboxylate
• Synonyms: benzyl (2S,3aS,7aS)-N-(tert-butoxycarbonyl)octahydroindole-2-carboxylate
• CAS NO: 960529-90-2
• Molecular Weight: 359.466
• Mol File: 960529-90-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl (2S,3aS,7aS)-N-(tert-butoxycarbonyl)octahydroindole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (2S,3aS,7aS)-N-(tert-butoxycarbonyl)octahydroindole-2-carboxylate(960529-90-2)
• EPA Substance Registry System: benzyl (2S,3aS,7aS)-N-(tert-butoxycarbonyl)octahydroindole-2-carboxylate(960529-90-2)

Safety Data

• Hazardous Substances Data: 960529-90-2(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 80828-13-3 (+/-)-(2S,3aS,7aS)-octahydroindole-2-carboxylic acid 
• 16851-56-2 indolin-2-yl carboxylic acid 
• 82717-91-7 (+/-)-benzyl (2S,3aS,7aS)-octahydroindole-2-carboxylate p-toluenesulfonic acid salt 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 109523-13-9 (2S,3aS,7aS)-1-(tert-butoxycarbonyl)octahydro-1H-indole-2-carboxylic acid 

Relevant articles and documents

Efficient access to N-protected derivatives of (R,R,R)- and (S,S,S)-octahydroindole-2-carboxylic acid by HPLC resolution

The preparation of the proline analogue (2S,3aS,7aS)-octahydroindole-2-carboxylic acid (Oic) and its enantiomer, (2R,3aR,7aR)-Oic, is described. A racemic precursor has been synthesized in good yield and subjected to HPLC resolution on a chiral column. The high efficiency of both the synthetic and chromatographic procedures has allowed the isolation of multigram quantities of each amino acid in enantiomerically pure form and suitably protected for use in peptide synthesis.