96287-28-4 Usage
General Description
(S)-Azetidine-2-carboxylic acid ethyl ester hydrochloride is a chemical compound that is used in the synthesis of pharmaceuticals and agrochemicals. It is an ester derivative of (S)-azetidine-2-carboxylic acid, which is an important building block in the production of various drugs and agricultural products. (S)-Azetidine-2-carboxylic acid ethyl ester hydrochloride is often used in the preparation of chiral intermediates for the synthesis of bioactive molecules. Its hydrochloride form makes it more stable and easier to handle in laboratory settings. Overall, (S)-Azetidine-2-carboxylic acid ethyl ester hydrochloride is a valuable chemical compound with important applications in the pharmaceutical and agricultural industries.
Check Digit Verification of cas no
The CAS Registry Mumber 96287-28-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,2,8 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 96287-28:
(7*9)+(6*6)+(5*2)+(4*8)+(3*7)+(2*2)+(1*8)=174
174 % 10 = 4
So 96287-28-4 is a valid CAS Registry Number.
96287-28-4Relevant articles and documents
Biocatalytic One-Carbon Ring Expansion of Aziridines to Azetidines via a Highly Enantioselective [1,2]-Stevens Rearrangement
Miller, David C.,Lal, Ravi G.,Marchetti, Luca A.,Arnold, Frances H.
supporting information, p. 4739 - 4745 (2022/03/27)
We report enantioselective one-carbon ring expansion of aziridines to make azetidines as a new-to-nature activity of engineered "carbene transferase" enzymes. A laboratory-evolved variant of cytochrome P450BM3, P411-AzetS, not only exerts unparalleled stereocontrol (99:1 er) over a [1,2]-Stevens rearrangement but also overrides the inherent reactivity of aziridinium ylides, cheletropic extrusion of olefins, to perform a [1,2]-Stevens rearrangement. By controlling the fate of the highly reactive aziridinium ylide intermediates, these evolvable biocatalysts promote a transformation which cannot currently be performed using other catalyst classes.
