96693-27-5

Basic information

• Product Name: (R)-2,2'-dichloromethyl-1,1'-binaphthyl
• Synonyms: (R)-2,2'-dichloromethyl-1,1'-binaphthyl
• CAS NO: 96693-27-5
• Molecular Weight: 351.275
• Mol File: 96693-27-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2,2'-dichloromethyl-1,1'-binaphthyl(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2,2'-dichloromethyl-1,1'-binaphthyl(96693-27-5)
• EPA Substance Registry System: (R)-2,2'-dichloromethyl-1,1'-binaphthyl(96693-27-5)

Safety Data

• Hazardous Substances Data: 96693-27-5(Hazardous Substances Data)

Upstream product

• 172748-15-1 7,22-dihydro-8,21-dioxa-tetranaphtho<2,1-b:1',2'-d:2'',1''-h:1''',2'''-j>cyclododecene 

Downstream Products

• 866394-07-2 (S,S)-f-binaphane 
• 13670-39-8 1-(4,5-dihydrooxazol-2-yl)propan-2-one 

Relevant articles and documents

The Williamson Reaction: A New and Efficient Method for the Alternate Reaction of 2,2'-Bis(bromomethyl)-1,1'-binaphthyl and 1,1'-Binaphthalene-2,2'-diol

Treatment of 2,2'-bis(bromomethyl)-1,1'-binaphthyl with 1,1'-binaphthalene-2,2'-diol (+)-(R)-1 and cesium or potassium carbonate in refluxing acetone, gave the diastereomeric dioxacyclophanes (-)-(R,S)-3a and (+)-(R,R)-3b, both obtained in high yield, and the cyclic tetraether (+)-(R,R,R,S)-4 as isolated side product.Boron tribromide-promoted ether cleavage of 3a and 3b gave optically pure (-)-S-2 and (+)-(R)-2, respectively, and the recovered diol (+)-(R)-1.Alternatively, the same reaction sequence furnished the resolved diols (-)-(S)-1 and (+)-(R)-1 from (R,S)-1 and (+)-R-2, as well as optically pure 2,2'-bis(chloromethyl)-1,1'-binaphthyl (+)-(R)-5 from the racemic dibromide (R,S)-2 by using boron trichloride for ether cleavage.