97512-83-9

Basic information

• Product Name: S-(phenylsulfonyl)-L-cysteine
• Synonyms: S-(phenylsulfonyl)-L-cysteine
• CAS NO: 97512-83-9
• Molecular Weight: 261.323
• Mol File: 97512-83-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: S-(phenylsulfonyl)-L-cysteine(CAS DataBase Reference)
• NIST Chemistry Reference: S-(phenylsulfonyl)-L-cysteine(97512-83-9)
• EPA Substance Registry System: S-(phenylsulfonyl)-L-cysteine(97512-83-9)

Safety Data

• Hazardous Substances Data: 97512-83-9(Hazardous Substances Data)

Upstream product

• 52-90-4 L-Cysteine 
• 873-55-2 sodium benzenesulfonate 
• 98-09-9 benzenesulfonyl chloride 
• 52-89-1 l-cysteine hydrochloride 
• 134469-02-6 S-nitroso-L-cysteine 

Downstream Products

• 13081-14-6 N⁵-((R)-3-(((R)-2-amino-2-carboxyethyl)disulfanyl)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine 
• 102837-27-4 S-Phenylsulphonyl-N-acetyl-L-cysteine 
• 18840-45-4 L-Cystein-D-penicillamin-disulfid 

Relevant articles and documents

SOME OBSERVATION CONCERNING THE S-NITROSO AND S-PHENYLSULPHONYL DERIVATIES OF L-CYSTEINE AND GLUTATHIONE

The preparation of the thiolsulphonate derivatives 3 and 7 of L-cysteine and glutathione, respectively, via their corresponding S-nitroso derivatives 2 and 6, is described.

Exploring new activating groups for reactive cysteine NCAs

Due to its ability to reversibly crosslink proteins, cysteine has a unique role as an amino acid in nature. For controlled, asymmetric formation of disulfides from two thiols, one thiol needs to be activated. While few activating groups for cysteine have been proposed, they are usually not stable against amines making them unsuitable for solid phase peptide synthesis or amine initiated polymerization of α-amino acid-N-carboxy-anhydrides (NCAs). In this Letter we describe a series of new thiol activated cysteines, as well as their NCAs and explore the link between electron deficiency of the leaving group and control over NCA polymerization.

Thiosulphonate derivatives of amino acids

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