97632-25-2Relevant articles and documents
Stereoselective synthesis of (Z)-1-alkylseleno-1-alkenes by Ni-catalyzed coupling reaction of (Z)-dialkylselenoethenes with organozinc halides
Huang, Xian,Sun, Ai Ming
, p. 2725 - 2731 (1997)
(Z)-Dialkylselenoethenes 2, prepared conveniently from the hydrozirconation of dialkylselenoacetylenes 1 with Cp2Zr (H)Cl in THF followed by protonolysis, react readily at -10°C in THF with organozinc halides in the presence of a catalytic amou
Ligand Control of E/Z Selectivity in Nickel-Catalyzed Transfer Hydrogenative Alkyne Semireduction
Richmond, Edward,Moran, Joseph
, p. 6922 - 6929 (2015/10/05)
A nickel-catalyzed transfer hydrogenative alkyne semireduction protocol that can be applied to both internal and terminal alkynes using formic acid and Zn as the terminal reductants has been developed. In the case of internal alkynes, the (E)- or (Z)-olefin isomer can be accessed selectively under the same reaction conditions by judicious inclusion of a triphos ligand.
Bidentate hydroxyalkyl NHC ligands for the copper-catalyzed asymmetric allylic substitution of allyl phosphates with grignard reagents
Magrez, Magaly,Le Guen, Yann,Basle, Olivier,Crevisy, Christophe,Mauduit, Marc
supporting information, p. 1199 - 1203 (2013/02/25)
Demonstrating their potential: Bidentate alkoxy NHC ligands have been used in the copper-catalyzed asymmetric allylic alkylation of allyl phosphates with Grignard reagents (see scheme). The method provides access to tertiary and quaternary chiral centers with high regio- and enantioselectivity. The system is also applied to the synthesis of chiral E,E-dienes, a key structural motif prevalent in natural products. Copyright
