97903-37-2

Basic information

• Product Name: 1,23-dihydroxy-24,25,26,27-tetranorvitamin D3
• Synonyms: 1,23-dihydroxy-24,25,26,27-tetranorvitamin D3;(1S)-1,23-dihydroxy-24,25,26,27-tetranorcalciol
• CAS NO: 97903-37-2
• Molecular Formula: C₂₃H₃₆O₃
• Molecular Weight: 360.53014
• Mol File: 97903-37-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 531.4°Cat760mmHg
• Flash Point: 234.6°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 1.64E-13mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: 1,23-dihydroxy-24,25,26,27-tetranorvitamin D3(CAS DataBase Reference)
• NIST Chemistry Reference: 1,23-dihydroxy-24,25,26,27-tetranorvitamin D3(97903-37-2)
• EPA Substance Registry System: 1,23-dihydroxy-24,25,26,27-tetranorvitamin D3(97903-37-2)

Safety Data

• Hazardous Substances Data: 97903-37-2(Hazardous Substances Data)

Usage

Synonyms

1,23(OH)2D3-26,23-lactone

Type

Synthetic derivative of vitamin D3

Structure

Formed by the addition of a hydroxyl group at the 1 and 23 positions of the vitamin D3 molecule, and the removal of the side chain at the 24,25,26, and 27 positions

Therapeutic Applications

Extensively studied for potential use in treating various autoimmune and inflammatory diseases

Anti-inflammatory Effects

Exhibits potent anti-inflammatory properties

Immunomodulatory Effects

Demonstrates immunomodulatory effects

Anti-cancer Properties

Suggested to have anti-cancer properties and may play a role in regulating cell growth and differentiation

Further Research

More research is needed to fully understand the therapeutic potential and mechanisms of action of this compound

InChI:InChI=1/C23H36O3/c1-15(10-12-24)20-8-9-21-17(5-4-11-23(20,21)3)6-7-18-13-19(25)14-22(26)16(18)2/h6-7,15,19-22,24-26H,2,4-5,8-14H2,1,3H3/b17-6+,18-7+/t15-,19-,20-,21+,22+,23-/m1/s1

Upstream product

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Relevant articles and documents

Efficient and scalable total synthesis of calcitroic acid and its 13C-labeled derivative

Calcitroic acid, the deactivated form of the physiological active vitamin D3 metabolite calcitrol, and its 13C labeled derivative has been synthesized starting from the commercially available Inhoffen-Lythgoe diol in 11 steps with an

The Seleno-acetal Route to 1α-Hydroxy-vitamin D Analogues: Synthesis of 24-Oxa-1α-hydroxy-vitamin D3, A Useful Vitamin D Metabolism Probe

Alkylation of the lithio-demethylseleno-derivative of seleno-acetal 11 with chloromethyl isopropyl ether is the key reaction in the synthesis of the 24-oxa analogue (M