97984-63-9Relevant articles and documents
Phosphorylation of Tyrosine and Tyr-Thr-Lys Tripeptide with Cyclohexylmethyl- and (Deuteromethyl)phosphonochloridates
Baygildiev, T. M.,Krylov, I. I.,Krylov, V. I.,Osipov, V. N.,Rodin, I. A.,Rybalchenko, I. V.,Yashkir, V. A.
, p. 619 - 623 (2020/07/02)
Abstract: Methods for phosphorylation of tyrosine and Tyr-Thr-Lys tripeptide with cyclohexylmethyl(deuteromethyl)phosphonochloridates have been developed. These products can be used as reference compounds in the analysis of blood plasma of patients presumably exposed to cyclohexylmethylphosphonofluoridate (cyclosarin) action. Conditions for the separation and purification of the synthesized intermediates by means of chromatography have been determined and optimized, allowing high-purity phosphorylated products at the final stage of the synthesis.
Esterification of unprotected a-Amino acids in ionic liquids as the reaction media
Biondini, Daniele,Brinchi, Lucia,Germani, Raimondo,Goracci, Laura,Savelli, Gianfranco
experimental part, p. 39 - 44 (2010/08/22)
Ionic liquid 1,3-dimethylimidazolium methanesulfonate was used to prepare a-amino acids benzylic esters from unprotected amino acids and benzyl chloride. Esterification of several amino acids was achieved with satisfactory yields: by-products can be removed by a simple work-up procedure to afford the pure product. The described method is simple, mild, rapid and save.
A Simple and Convenient Method for Esterification of Tryptophan and Other Amino Acids
Arai, Isamu,Muramatsu, Ichiro
, p. 121 - 123 (2007/10/02)
-
