98983-40-5 Usage
General Description
9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one, also known as F-ara-A or Fludarabine, is a synthetic, purine nucleoside analog and an antineoplastic agent. It is used extensively in treatments for hematological malignancies such as chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma. The chemical works by interfering with DNA synthesis, thereby stopping the growth of cancer cells. It is activated by deoxycytidine kinase and is then converted into its active form fludarabine triphosphate, which leads to cell death. Despite its effectiveness, adverse side effects like bone marrow suppression, and neurological complications limit its usage. 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one is generally administered through injection or intravenous infusion.
Check Digit Verification of cas no
The CAS Registry Mumber 98983-40-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,9,8 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 98983-40:
(7*9)+(6*8)+(5*9)+(4*8)+(3*3)+(2*4)+(1*0)=205
205 % 10 = 5
So 98983-40-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H11FN4O4/c11-5-7(17)4(1-16)19-10(5)15-3-14-6-8(15)12-2-13-9(6)18/h2-5,7,10,16-17H,1H2,(H,12,13,18)/t4-,5+,7-,10-/m1/s1
