99-54-7 Usage
Chemical Properties
colourless to yellow crystals or beige powder
Uses
Different sources of media describe the Uses of 99-54-7 differently. You can refer to the following data:
1. 1,2-Dichloro-4-nitrobenzene is an intermediate in the synthesis of agrochemicals. Studies have been conducted to use 1,2-Dichloro-4-nitrobenzene as an organic intermediate for the synthetic preparati
on of ciprofloxacin (C482500).
2. 1,2-Dichloro-4-nitrobenzene is an intermediate in the synthesis of agrochemicals. Studies have been conducted to use 1,2-Dichloro-4-nitrobenzene as an organic intermediate for the synthetic preparation of ciprofloxacin (C482500).
Synthesis Reference(s)
The Journal of Organic Chemistry, 42, p. 3494, 1977 DOI: 10.1021/jo00442a009
General Description
Colorless crystals or light beige solid.
Air & Water Reactions
Insoluble in water.
Fire Hazard
3,4-Dichloronitrobenzene is combustible.
Flammability and Explosibility
Nonflammable
Purification Methods
Crystallise it from absolute EtOH. [Beilstein 5 IV 726.]
Check Digit Verification of cas no
The CAS Registry Mumber 99-54-7 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 9 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 99-54:
(4*9)+(3*9)+(2*5)+(1*4)=77
77 % 10 = 7
So 99-54-7 is a valid CAS Registry Number.
99-54-7Relevant articles and documents
Doyle et al.
, p. 3494 (1977)
Nitration of deactivated aromatic compounds via mechanochemical reaction
Wu, Jian-Wei,Zhang, Pu,Guo, Zhi-Xin
supporting information, (2021/05/05)
A variety of deactivated arenes were nitrated to their corresponding nitro derivatives in excellent yields under high-speed ball milling condition using Fe(NO3)3·9H2O/P2O5 as nitrating reagent. A radical involved mechanism was proposed for this facial, eco-friendly, safe, and effective nitration reaction.
Completely-continuous flow synthesis method of 3,4-dichloronitrobenzene under action of catalyst
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Paragraph 0070-0082, (2020/05/30)
The invention discloses a completely-continuous flow synthesis method of 3,4-dichlonitrobenzene under the action of a catalyst. The completely-continuous flow synthesis method is carried out in an integrated completely-continuous flow reaction system, a reaction substrate and other raw materials are uninterruptedly added at a feed port, the product 3, 4-dichloronitrobenzene is uninterruptedly obtained at a discharge port, and the synthesis method is safe and efficient and has no amplification effect. Compared with a traditional production method, the method of the invention has the advantagesof shortening of the production time to be within 120 seconds, no amplification effect, stable product index and good reproducibility.
