99209-26-4

Basic information

• Product Name: Benzaldehyde, 4-(1-octynyl)-
• CAS NO: 99209-26-4
• Molecular Formula: C15H18O
• Molecular Weight: 214.307
• Mol File: 99209-26-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 4-(1-octynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-(1-octynyl)-(99209-26-4)
• EPA Substance Registry System: Benzaldehyde, 4-(1-octynyl)-(99209-26-4)

Safety Data

• Hazardous Substances Data: 99209-26-4(Hazardous Substances Data)

Upstream product

• 113794-23-3 tributyl(oct-1-yn-1-yl)stannane 
• 1122-91-4 4-bromo-benzaldehyde 
• 629-05-0 n-octyne 
• 15164-44-0 p-(iodophenyl)carboxaldehyde 

Downstream Products

• 99209-58-2 4-(1'-n-octynyl)benzyl alcohol 
• 1426121-84-7 C₃₈H₆₂N₂ 
• 883453-71-2 3-nitro-4-octylbenzaldehyde 
• 49763-66-8 4-octylbenzaldehyde 

Relevant articles and documents

RATIONALLY DESIGNED LAWSONE DERIVATIVES AS ANTIMICROBIALS AGAINST MULTIDRUG-RESISTANT STAPHYLOCOCCUS AUREUS

Naphthoquinone derivatives of Lawsone have been found to be effective against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). Such compounds generally contain a substituent group at the 3-position of a specific naphthoquinone compound, i.e. 2-hydroxy-1,4-naphthoquinone. One of these derivatives referred to as compound 6c in the series exhibits potent antimicrobial activity that is comparable to that of the two commercial antibiotics ofloxacin and ciprofloxacin against the two strains of methicillin sensitive Staphylococcus aureus (MSSA; ATCC 29213 and ATCC 6538). In the case of two strains of MRSA (ATCC BAA-44 and ATCC BAA-1717) that have developed drug resistance to both ofloxacin and ciprofloxacin, the antimicrobial activity of 6c can almost rival that of vancomycin and daptomycin. Furthermore, 6c is also effective against vancomycin-intermediate and daptomycin non-susceptible strain of MRSA (ATCC 700699). Besides the efficacy, 6c has a much improved drug resistance profile in comparison with the conventional antibiotics.

Aqueous Sonogashira coupling of aryl halides with 1-alkynes under mild conditions: Use of surfactants in cross-coupling reactions

Aqueous Sonogashira coupling between lipophilic terminal alkynes and aryl bromides or iodides gave moderate to high yields at 40°C using readily available and inexpensive surfactants (2.0 w/v% in water) such as SDS and CTAB. The catalyst precursor was 2 m

Antimycobacterial activity evaluation, time-kill kinetic and 3D-QSAR study of C-(3-aminomethyl-cyclohexyl)-methylamine derivatives

A series of C-(3-aminomethyl-cyclohexyl)-methylamine derivatives were synthesized and evaluated for their antitubercular activity. Some of the compounds exhibited potent activity against Mycobacterium tuberculosis H37Rv. One of the compound having t-butyl at para position of the benzene ring showed excellent activity even better than the standard drug ethambutol with MIC value 1.1 ± 0.2 μM. The time-kill kinetics study of two most active compounds showed rapid killing of the M. tuberculosis within 4 days. Additionally atom-based quantitative structure-activity relationship (QSAR) model was developed that gave a statistically satisfying result (R2) = 0.92, Q2 = 0.75, Pearson-R = 0.96 and effectively predicts the anti-tuberculosis activity of training and test set compounds.