99782-78-2Relevant articles and documents
Design and synthesis of lipid-coupled inositol 1,2,3,4,5,6-hexakisphosphate derivatives exhibiting high-affinity binding for the HIV-1 MA domain
Tateishi, Hiroshi,Anraku, Kensaku,Koga, Ryoko,Okamoto, Yoshinari,Fujita, Mikako,Otsuka, Masami
, p. 5006 - 5022 (2014/07/07)
The precursor of Gag protein (Pr55Gag) of human immunodeficiency virus, the principal structural component required for virus assembly, is known to bind d-myo-phosphatidylinositol 4,5-bisphosphate (PIP2). The N-terminus of Pr55G
Tetrakisphosphates and Bispyrophosphates of myo-Inositol Derivatives as Allosteric Effectors of Human Hemoglobin: Synthesis, Molecular Recognition, and Oxygen Release
Koumbis, Alexandros E.,Duarte, Carolina D.,Nicolau, Claude,Lehn, Jean-Marie
, p. 169 - 180 (2013/01/09)
Various 2,5- and 1,4-substituted and unsubstituted myo-inositol tetrakisphosphates and bispyrophosphates were prepared following a general synthetic pathway. All final compounds were tested for their capability to induce oxygen release from human hemoglob
Total synthesis of myo-inositol polyphosphates from benzene via conduritol B derivatives
Carless, Howard A. J.,Busia, Kofi
, p. 3449 - 3452 (2007/10/02)
The four (±)-myo-inositol phosphates 1,4,5-IP3 (1), 2,4,5-IP3 (15), 1,2,4,5-IP4 (17) and 4,5-IP2 (19) have been synthesised from benzene, using the protected conduritol B (10) as the key intermediate.