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l-ASPARAGINASE (9015-68-3)

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Chemistry
Product Name: ASPARAGINASE
Synonyms: L-ASPARAGINE AMIDOHYDROLASE;ADENOSINE DEAMINASE;colaspase;crasnitin;L-ASPARAGINASE;IUB: 3.5.4.4;ASPARAGINASE;EC 3.5.1.1;
The Molecular formula of l-ASPARAGINASE(9015-68-3): C14H17NO4S
The Molecular Weight of l-ASPARAGINASE(9015-68-3): 295.35
EINECS: 232-765-3
storage temp.: 2-8°C
form: suspension
Toxicity Data With Reference
1.    

ims-chd TDLo:8145 iu/kg/1 W:SYS

    CANCAR    Cancer. 34 (1974),780.
2.    

ipr-rat LD50:8204 mg/kg

    YIKUAO    Yamaguchi Igaku. 18 (1969),271.
3.    

scu-rat LD50:8204 mg/kg

    YIKUAO    Yamaguchi Igaku. 18 (1969),271.
4.    

ivn-rat LD50:7568 mg/kg

    YIKUAO    Yamaguchi Igaku. 18 (1969),271.
5.    

ivn-dog LD50 50,000 iu/kg

    RRCRBU    Recent Results in Cancer Research. 33 (1970),174.
6.    

ivn-cat LD50 50,000 iu/kg

    RRCRBU    Recent Results in Cancer Research. 33 (1970),174.
7.    

ivn-rbt LDLo 500 iu/kg

    RRCRBU    Recent Results in Cancer Research. 33 (1970),174.
Safety Profile
Human (child) systemic effects by intramuscular route. An experimental teratogen. Other experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data.
The Hazard Codes of l-ASPARAGINASE(9015-68-3) :   T,   Xn
The Risk Statements information of l-ASPARAGINASE(9015-68-3):
61:  May cause harm to the unborn child 
62:  Possible risk of impaired fertility 
63:  Possible risk of harm to the unborn child 
61:  May cause harm to the unborn child  
63:  Possible risk of harm to the unborn child 
42/43:  May cause sensitization by inhalation and skin contact 
The Safety Statements information of l-ASPARAGINASE(9015-68-3):
22:  Do not breathe dust 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
53:  Avoid exposure - obtain special instruction before use 
36/37:  Wear suitable protective clothing and gloves 
36/37/39:  Wear suitable protective clothing, gloves and eye/face protection 
RIDADR: 3249
WGK Germany: 3
RTECS: CI9000000
F: 10-21