1,3,4-Oxadiazole, 2-phenyl-

CAS  

 825-56-9

SYNONYMS  

 * 2-Fenil-1,3,4-ossadiazolo
* 2-Phenyl-1,3,4-oxadiazole

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RO0811300
CHEMICAL NAME           : 1,3,4-Oxadiazole, 2-phenyl-
CAS REGISTRY NUMBER     : 825-56-9
BEILSTEIN REFERENCE NO. : 0118804
REFERENCE               : 4-27-00-07140 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H6-N2-O
MOLECULAR WEIGHT        : 146.16
WISWESSER LINE NOTATION : T5NN DOJ CR
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Fenil-1,3,4-ossadiazolo
   * 2-Phenyl-1,3,4-oxadiazole
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 440 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 121,443,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 387 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 13,629,1958
 
                            *** END OF RECORD ***