Welcome to LookChem.com Sign In | Join Free   Post buying lead  Chemical Tools
Post Buying Lead

Basic information

  • Name:
  • Phenol,4,4'-[(1-methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)-

  • Superlist Name:
  • Probucol
  • CAS No.:
  • 23288-49-5

  • Formula:
  • C31H48O2S2
  • Synonyms:
  • Acetone,bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole (8CI);Phenol, 4,4'-(isopropylidenedithio)bis[2,6-di-tert-butyl-(8CI);4,4'-(Isopropylidenedithio)bis[2,6-di-tert-butylphenol];Biphenabid;Bisbid;Bisphenabid;DH 581;Lipomal;Lorelco;Lurselle;NSC 652160;NSC 86225;Panavir;Phenbutol;Probucol;Sinlestal;
Supplier Location:
China (Mainland)(11)Taiwan(1)
Business Type:
Importer/Exporter(12)
Certificates:
ISO(1)QS(1)Production License(0)

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Chemistry

Probucol(23288-49-5) is an anti-hyperlipidemic drug initially developed in the treatment of coronary artery disease.
However, clinical trials were stopped after it was found that it causes long QT syndrome in patients.
Probucol(23288-49-5) was initially developed in the 1970s by a chemical company to maximize airplane tire longevity.
The molecular formula of Probucol is C31H48O2S2 and its formula weight is 516.84.
The density of Probucol(23288-49-5) is 1.07 g/cm3 . The boiling point is  546.7 °C at 760 mmHg. The refractive index is about  1.573. Its flash point is  264.9 °C.
The chemical synonyms of Probucol(23288-49-5) are PROBUCOL;4,4’-((1-methylethylidene)bis(thio))bis(2,6-bis(1,1-dimethylethyl)-pheno;biphenabid;bisbid;bisphenabid;dh581;4,4'-ISOPROPYLIDINEDITHIO-BIS-(2,6-DI-TERT-BUTYL)PHENOL;4-({1-[(4-hydroxy-3,5-di-t-butylphenyl)thio]-1-methylethyl}thio)-2,6-di-t-butylphenol
The molecular structure of Probucol(23288-49-5):

Uses

Used to lower levels of cholesterol in the blood.

Standards and Recommendations

Probucol lowers the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism. Additionally, probucol may inhibit cholesterol synthesis and delay cholesterol absorption. Probucol is a powerful antioxidant which inhibits the oxidation of cholesterol in LDLs; this slows the formation of foam cells, which contribute to atherosclerotic plaques.

It is believed to act at ABCA1.

It also lowers levels of HDL.

Specification

Stability
Stable at normal temperatures and pressures.

Decomposition
Carbon monoxide, Carbon dioxide, Sulfur oxides.

©2008 LookChem.com,License:ICP NO.:Zhejiang10014259

[Hangzhou]86-571-85317600,85317603,85317620