103577-45-3 C16H14F3N3O2S Lansoprazole CAS NO.103577-45-3

lansoprazole basic information

product name:	lansoprazole
synonyms:	1h-benzimidazole,2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)su;2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1h-benz;lfinyl)-;prevacid;ogast;lansoprazole;lansaprazole;lansox
cas:	103577-45-3
mf:	c16h14f3n3o2s
mw:	369.36
einecs:
product categories:	active pharmaceutical ingredients;intermediates & fine chemicals;pharmaceuticals;sulfur & selenium compounds;ion pump inhibitors;monovalent ion channels;voltage-gated ion channels;atpase;pharmaceutical intermediates;api reference standardfree base api;other apis;pharmaceutical
mol file:	103577-45-3.mol

lansoprazole chemical properties

mp	178-182°c dec.
storage temp.	2-8°c
form	powder
color	off-white
cas database reference	103577-45-3(cas database reference)

safety information

hazard codes	xi
risk statements	36/37/38
safety statements	26-36
wgk germany	2
rtecs	dd9487500
hazardous substances data	103577-45-3(hazardous substances data)

msds information

lansoprazole usage and synthesis

chemical properties	white crystalline powder
usage	used as a gastric proton pump inhibitor. an antiulcerative
usage	anthelmintic
usage	a h+,k+-atpase inhibitor that displays antisecretory activity
usage	treatment of gastroesophageal reflux disease (gerd), erosive esophagitis, duodenal ulcers, helicobacter pylori (h. pylori) infections,stomach ulcers, prevention of stomach ulcers in those people taking non-steroidal anti-inflammatory drugs (nsaids), such
usage	for the treatment of acid-reflux disorders (gerd), peptic ulcer disease, h. pylori eradication, and prevention of gastroinetestinal bleeds with nsaid use.
biological activity	h + ,k + -atpase inhibitor (ic 50 = 6.3 μ m) that displays antisecretory and antiulcer activity. inhibits gastric acid secretion (ic 50 = 0.09 μ m for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. antibacterial against helicobacter pylori in vitro . also blocks swelling-dependent chloride channel (iciswell) in nih3t3 fibroblasts. more potent than omeprazole (5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1h-benzimidazole ).

lansoprazole preparation products and raw materials

raw materials

acetic acid glacial-->thionyl chloride-->acetic anhydride-->tert-butanol-->vanadium pentoxide -->2,3-lutidine-->2-mercaptobenzimidazole

hennan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion, the com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .

sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others . these products have been being well exported to europe , southeast asia , the middle east , africa , south america and some other countries and areas.

we sincerely welcome foreign friends to visit our plant for cooperation. with the idea of "quality first,credit priority, excellent service", we are highly acknowledged by customers for good quality and competitive price. more importantly , the company has a strong r & d team, who are professional engineers and scholars with ph. d. .so we are confident to serve you better with our high - quality products and professional team.

we are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market. we welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!