13422-55-4 C63H91CoN13O14P Mecobalamin CAS NO.13422-55-4

mecobalamin basic information

pharmacological action application

product name:	mecobalamin
synonyms:	mecobalamin;mecobalamine;methylcobalamin;cobalt-methylcobalamin;cobinamide,cobalt-methylderivative,hydroxide,dihydrogenphosphate(ester),;innersalt,3’-esterwith5,6-dimethyl-1-alpha-d-ribofuranosylbenzimidazole;mbl-a;methycobal
cas:	13422-55-4
mf:	c63h91con13o14p
mw:	1344.38
einecs:	236-535-3
product categories:	pharmaceuticals;nutritional supplements;intermediates & fine chemicals;vitamin b12;nutrition research;vitamins;vitamin ingredients;api
mol file:	13422-55-4.mol

mecobalamin chemical properties

mp	>190°c (dec.)
storage temp.	−20°c

safety information

hazard codes	xi
risk statements	36/37/38
safety statements	24/25-36-26
wgk germany	2
rtecs	gg3745000

msds information

mecobalamin usage and synthesis

pharmacological action	mecobalamin as vitamin b12 derivatives, should be called "methyl vitamin b12" according to the chemical structure of name, the functional groups of methylation can be involved in the biochemical process of methyl transfer activity, promoting to nucleic acid of nerve tissue, the metabolism of protein and fat, , can stimulate the synthesis of lecithin schwann cells, repairing the damaged myelin, improving nerve conduction velocity; directly into nerve cells, and stimulating axon regeneration of damaged area; stimulating protein synthesis in nerve cells and enhanced synthetic metabolism of axons to prevent axonal degeneration; involved in nucleic acid synthesis, promoted hematopoietic function. the treatment is clinically used in diabetic neuropathy, long-term use of macrovascular complications of diabetes are the curative effect. mecobalamin is used for peripheral nerve disorders treatment drug, compared with other vitamin b12 preparations, having good transfer on the nervous tissue, through the methyl transfer reaction, can promote nucleic acid, protein lipid metabolism, repairing the damaged nerve tissue. in homocysteine synthetic egg ammonia acid process, it plays a role of coenzyme, especially by deoxyuridine synthesis of thymidine, promoting dna and rna synthesis of participation. also in the experiment of glial cells, the drugs can improve methionine synthase activity and promote the synthesis of myelin lipids lecithin. improving the nerve tissue metabolism, can promot axis cable and protein synthesis, make the delivery rate of the skeletal protein close to normal, maintain axonal functions. besides mecobalamin injections can inhibit nerve tissue of abnormal impulse conduction, promoting redl blood cells mature, split, improving anemia. mecobalamin can be quickly restored due to lack of b12 and reduce the number of rat erythrocytes, hemoglobin, hematocrit value. used for megaloblastic red blood cell anemia and peripheral nerve disorder due to the lack of vitamin b12. the above information is edited by the chemicalbook hanya.
application	1.it is used for the treatment of nervous system diseases, relieving pain and numbness, speeded relieving pain, improving pain caused by cervical spondylosis, treatment of sudden deafness, etc. 2.methylcobalamin is a kind of endogenous coenzyme b12, participating in the one carbon unit cycle, playing an important role in the synthesis of methionine homocysteine methyl transfer reaction process.
chemical properties	dark red crystalline powder
usage	one of the biologically active forms of vitamin b12; differing only by the substitution of a methyl for the cyano group. coenzyme required in the biosynthesis of methionine. vitamin (hematopoietic).
usage	histamine receptor, alzheimer research

mecobalamin preparation products and raw materials

raw materials

cyanocobalamin

hennan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion, the com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .

sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others . these products have been being well exported to europe , southeast asia , the middle east , africa , south america and some other countries and areas.

we sincerely welcome foreign friends to visit our plant for cooperation. with the idea of "quality first,credit priority, excellent service", we are highly acknowledged by customers for good quality and competitive price. more importantly , the company has a strong r & d team, who are professional engineers and scholars with ph. d. .so we are confident to serve you better with our high - quality products and professional team.

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