153439-40-8 Fexofenadine hydrochloride CAS NO.153439-40-8

fexofenadine hydrochloride basic informationdescription references
product name:fexofenadine hydrochloridesynonyms:fexofenadine-d10 hcl;α,α-dimethyl-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]benzeneacetic acid;benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride;mdl 16455a;telfast;telfast bd;2-[4-[1-hydroxy-4-[4-(hydroxy-diphenyl-methyl)-1-piperidyl]-butyl]phenyl]-2-methyl-propanoic acid hydrochloride;allegracas:153439-40-8mf:c32h40clno4mw:538.12einecs:product categories:intermediates & fine chemicals;metabolites;pharmaceuticals;aromatics;heterocycles;metabolites & impurities;apimol file:153439-40-8.mol
fexofenadine hydrochloride chemical properties
melting point 148-150ocstorage temp. −20°ccas database reference153439-40-8(cas database reference)
safety information
hazard codes xirisk statements 36/37/38safety statements 26-36
msds information
fexofenadine hydrochloride usage and synthesis
descriptionfexofenadine hydrochloride (trade name: allegra) belongs to a second-generation antihistamine pharmaceutical drug. it is mainly used for the treatment of allergy symptoms including watery eyes, hay fever, nasal congestion, urticaria, runny nose, itching eyes/nose, sneezing, hives, and itching. it is a kind of selectively peripheral h1 blocker. its mechanism of action in vivo is through preventing the histamine-mediated activation of the h1 receptors, thus alleviating the symptoms related to allergy. compared to the first-generation antihistamine drug, it is less prone to penetrate the blood-brain barrier, reducing the possibility to cause side effects such as drowsiness.referenceshttp://www.rxlist.com/allegra-drug/consumer-uses.htm
# propertiesoff-white crystalline solidusagea metabolite of of terfenadine, a h1-histamine receptor antagonistusagethe active metabolite of terfenadine (t114500), a h1-histamine receptor antagonist.usageantihistaminic;histamine h1-receptor antagonistbiological activityselective histamine h 1 receptor antagonist (pk i = 8.1). active metabolite of terfenadine that displays non-sedating antiallergic effects.牋.