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HENAN SUNLAKE ENTERPRISE CORPORATION191732-72-6//file1.lookchem.com/300w/synthetic/2022-02-02-04/557182e5-dab3-42f8-886b-23b62bf78a0f.png
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191732-72-6 CAS NO.191732-72-6

Min.Order Quantity:
100 Gram
Purity:
98.5%
Port:
Shanghai Port
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

  • Lenalidomide
  • Lenalidomide supplier
  • Lenalidomide factory

Quick Details

  • ProName: 191732-72-6
  • CasNo: 191732-72-6
  • Molecular Formula: C13H13N3O3
  • Appearance: Yellow solid
  • Application: pharmaceutical uses
  • DeliveryTime: 7-10 working days
  • PackAge: Sealed aluminum foil package
  • Port: Shanghai Port
  • ProductionCapacity: 100 Kilogram/Week
  • Purity: 98.5%
  • Storage: Protected from light, stored hermetica...
  • Transportation: By air or courier or sea
  • LimitNum: 100 Gram
  • Molecular Weight: 259.26062

Superiority

henan sunlake enterprise corporation

our company advantages:

1、the highest quality with the competitive price.

2、professional human services.

3、the fastest and safest delivery service.

4、the faster and safest delivery service.

5、the high purity products.

6、we have a sufficient supply of stock.

7、a variety of payments, such as l/c, tt, , moneygram or other payments.

company information

henan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion. the com[any was established in june. 1998, until now having more than 18 years experience in manufacturing & exporting chemical raw material .

sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others. these products have been being well exported to europe, southeast asia, the middle east ,africa, south america and some other countries and areas.

we sincerely welcome foreign friends to visit our plant for cooperation. with the idea of "quality first,credit priority, excellent service", we are highly acknowledged by customers for good quality and competitive price. more importantly , the company has a strong r & d team, who are professional engineers and scholars with ph. d. .so we are confident to serve you better with our high - quality products and professional team. we are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional supplier in international market.

we welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!

Details

lenalidomide basic information

antitumor drug
product name: lenalidomide
synonyms: lenalidomide;3-(7-amino-3-oxo-1h-isoindol-2-yl)piperidine-2,6-dione;lenalidomidelenalidomide; 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline;3-(4-amino-1,3-dihydro-1-oxo-2h-isoindol-2-yl)-2,6-piperidinedione;cc-5013;revlimi;lenalidomide(other anti-cancers)
cas: 191732-72-6
mf: c13h13n3o3
mw: 259.26062
einecs:
product categories: molecular targeted antineoplastic;intermediates & fine chemicals;pharmaceuticals;amines;heterocycles;inhibitor;cc-5013;inhibitors
mol file: 191732-72-6.mol
lenalidomide structure
lenalidomide chemical properties
mp 269-271°c
storage temp. -20°c freezer
cas database reference 191732-72-6(cas database reference)
safety information
hazardclass irritant
msds information
lenalidomide usage and synthesis
antitumor drug lenalidomide is a kind of antitumor drugs that developed by american biological pharmaceutical companies. its chemical structure is similar with thalidomide. it has many functions such as anti-tumor, immune regulation and anti-angiogenesis. it can inhibit the secretion of inflammatory cytokines, and increase the secretion of peripheral blood mononuclear anti-inflammatory cytokines. vitro tests show that lenalidomide can inhibit the hyperplasia of some cell lines such as namalwa cell. it can inhibit the growth of patients’ multiple myeloma cells and mm1s cell. in addition, lenalidomide also can inhibit the expression of oxidase-2 (cox-2), but it has no effect on cox-1. two multicenter randomized double-blind placebo-controlled clinical studies evaluate the safety and curative effect of lenalidomide that is used for multiple myeloma. the primary efficacy end point of the studies is time to progression (ttp). the interim analysis shows that ttp of the combination group is significantly superior to dexamethasone group. recent clinical research results show that lenalidomide not only has curative effect on treating mds and mm, but also on treating myeloma, leukemia, metastatic renal cell carcinoma, solid tumor, idiopathic generalized amyloidosis and systemic bone marrow fibrosis disease with marrow unripe.
lenalidomide is a new derivative of thalidomide. but its teratogenic toxicity has not found. its effectiveness is 100 times stronger than thalidomide. according to the result of three clinical trials, lenalidomide is the most effective drug in the treatment of multiple myeloma. more than half of patients can prolong survival time to more than 3 years after taking the drug. in addition, it is also the only effective drugs to treat myelodysplastic syndrome (mds). clinical results find that 64% of the patients with mds need not use blood transfusion after treated by lenalidomide.
in december 2005, the us food and drug administration (fda) approved lenalidomide to be used in the treatment of myelodysplastic syndrome (mds).
in march 2006, the fda approved lenalidomide that was produced by american celgene biological pharmaceutical companies to be used in the treatment of multiple myeloma (mm).
on september 23, 2011, the european medicines agency (ema) released information that they have confirmed that the benefits of lenalidomide(trade name: revlimid) to be used in the treatment of patients group that was approved outweighed the risks. meanwhile they warned the doctor the risk of the drug to cause new cancer cases. lenalidomide has been used with dexamethasone to treat adult patients with multiple myeloma that has received at least one treatment. three new studies show that the incidence of new cancer will be increased in the patients with newly diagnosed multiple myeloma treated by lenalidomide and other combined treatment increased incidence of cancer.
the above information is edited by the chemicalbook geqian.
chemical properties yellow solid
usage immunomodulatory drug; analog of thalidomide.
usage lenalidomide (revlimid, cc-5013) is a tnf-α secretion inhibitor with ic50 of 13 nm.
usage lovastatin content <1% 98%
usage a thalidomide analog known to have immunomodulatory properties

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