302962-49-8 Dasatinib CAS NO.302962-49-8

dasatinib basic information
product name: dasatinib
synonyms: dasatinib(bms-354825);bms-354825;n-[2-chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide;5-thiazolecarboxamide, n-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-;dasatinib;n-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide;n-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide;2-{6-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-2-methyl-pyrimidin-4-ylamino}-thiazole-5-carboxylic acid (2-chloro-6-methyl-phenyl)-amide
cas: 302962-49-8
mf: c22h28cln7o3s
mw: 488.01
einecs:
product categories: intermediates & fine chemicals;pharmaceuticals;tyrosine kinase inhibitors;pharmaceutical intermediate;inhibitor;sprycel;anti-cancer&immunity;inhibitors
mol file: 302962-49-8.mol
dasatinib structure
dasatinib chemical properties
mp 275-286°c
storage temp. -20°c freezer
cas database reference 302962-49-8(cas database reference)
safety information
msds information
dasatinib usage and synthesis
chemical properties pale-yellow solid
usage a new, oral, small-molecule tyrosine kinase inhibitor (tki) for the treatment of cml. antineoplastic
usage dasatinib is a novel, potent and multi-targeted inhibitor that targets abl, src and c-kit, with ic50 of ＜1 nm, 0.8 nm and 79 nm, respectively.
dasatinib preparation products and raw materials

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