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HENAN SUNLAKE ENTERPRISE CORPORATION378-44-9 C22H29FO5 Betamethasone//file1.lookchem.com/cas/reactions/2021/05/26/3176546.png
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378-44-9 C22H29FO5 Betamethasone CAS NO.378-44-9

FOB Price:
USD 1.00-1.00 /Kilogram Get Latest Price
Min.Order Quantity:
1 Kilogram
Purity:
99%
Port:
China main ports
Payment Terms:
L/C,T/T,MoneyGram,Other

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Product Details

Keywords

  • 378-44-9
  • 378-44-9
  • 378-44-9

Quick Details

  • ProName: 378-44-9 C22H29FO5 Betamethasone
  • CasNo: 378-44-9
  • Molecular Formula: C22H29FO5
  • Appearance: white powder
  • Application: 378-44-9
  • DeliveryTime: Promopt .
  • PackAge: 1g;5g;10g;25g;50g;100g;500g;1KG;5KG,25...
  • Port: China main ports
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 99%
  • Storage: Room temperature with sealed well
  • Transportation: by air /by sea /by courier
  • LimitNum: 1 Kilogram
  • Valid Period: 6 month
  • Application: Multipurpose intermediate
  • Certification: ISO/9001 Certificate

Superiority

1. certificate of analysis (coa)

2. material safety data sheet (msds)

3. route of synthesis (ros)

4. method of aanlysis (moa)

5. nuclear magnetic resonance (nmr)

6. packing pictures and loading video before loading

7. free sample

9. factory audit

10. strong after-sale service

betamethasone basic information
hormone drugs chemical properties application production method category toxicity grading acute toxicityflammability and hazard characteristics storage characteristics extinguishing agent
product name: betamethasone
synonyms: (11beta,16beta)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione;16-beta-methyl-1,4-pregnadiene-9-alpha-fluoro-11-beta,17-alpha,21-triol-3,20;16-beta-methyl-1,4-pregnadiene-9-alpha-fluoro-11-beta,17-alpha,21-triol-3,20-dione;17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-9-alpha-fluoro-11-bet;6beta)-;9-alpha-fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione;9-alpha-fluoro-11-beta,17-alpha,21-trihydroxy-16-beta-methylpregna-1,4-diene;9-alpha-fluoro-16-beta-methyl-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20
cas: 378-44-9
mf: c22h29fo5
mw: 392.46
einecs: 206-825-4
product categories: biochemistry;hydroxyketosteroids;steroids;intermediates & fine chemicals;pharmaceuticals;steroid and hormone;pharmaceutical intermediate;celestone
mol file: 378-44-9.mol
betamethasone structure
betamethasone chemical properties
mp 235-237°c
refractive index 118 ° (c=1, dioxane)
storage temp. 0-6°c
merck 1180
cas database reference 378-44-9(cas database reference)
nist chemistry reference pregna-1,4-diene-3,20-dione, 9alpha-fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl-(378-44-9)
safety information
hazard codes xi,xn,t
risk statements 40-48/20/21-61
safety statements 22-36-45-53
rtecs tu4000000
hs code 29379000
hazardous substances data 378-44-9(hazardous substances data)
msds information
betamethasone usage and synthesis
hormone drugs betamethasone, belongs to adrenal corticosteroids, it is a isomer of dexamethasone , and the role of betamethasone is similiar to prednisolone and dexamethasone , it has anti-inflammatory, anti-rheumatic, anti-allergic and suppression of the immune and other pharmacological effects, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone etc. , it can reduce and prevent tissue response to inflammation and eliminate heat, redness and swelling caused by local non-infectious inflammation, thereby reducing the performance of inflammation, anti-inflammatory effect of this product 0.3mg is equal to dexamethasone 0.75mg, prednisone 5mg or 25mg cortisone .
betamethasone sodium retention effect is a hundred times more than hydrocortisone, in primary adrenal hypofunction, it can be used together with glucocorticoid for replacement therapy ,and it is used for preventing or inhibiting cell-mediated immune response, delaying allergic reactions and reducing the primary immune response expansion ,it is used for low renin and low aldosterone syndrome and autonomic neuropathy induced orthostatic hypotension.
currently betamethasone is also used for the treatment of active rheumatoid arthritis, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, atopic dermatitis, eczema, neurodermatitis, seborrheic dermatitis, and pruritus and comprehensive treatment of certain infections.
the product is contraindicated in severe psychiatric history, active duodenal ulcer, recent gastrointestinal anastomosis, heavier osteoporosis, overt diabetes, severe hypertension, virus , bacterial, fungal infections which are failed to control by the use of antimicrobial agents , thrombophlebitis, skin infections, such as impetigo, tinea, jock itch and so on.
the above information is edited by the chemicalbook of tian ye.
chemical properties white crystalline powder. mp 231-234 deg.] c (decomposition). odorless. acetate betamethasone ([987-24-6]) is also white crystalline powder, melting point 205-208 ℃, slightly soluble in alcohol, ethanol, and very slightly soluble in chloroform or ether, insoluble in water, odorless.
application hormone drugs.it is mainly used for anti-inflammatory and anti-allergic. it is suitable for rheumatoid arthritis and various skin diseases. betamethasone role is similiar to dexamethasone, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone and it has few side effects.
production method according to u.s. patent no. 3,164,618, betamethasone acetate is dealt with hydrochloric acid in methanol - chloroform - water mixture , it can be converted to betamethasone.
category toxic substances
toxicity grading middle toxic
acute toxicity oral -mouse ld50:> 4500 mg / kg
flammability and hazard characteristics combustible;its combustion produces toxic fumes of fluoride.
storage characteristics ventilated, low-temperature ,dry storeroom.
extinguishing agent dry powder , foam, sand, carbon dioxide, water spray.
chemical properties white to off-white solid
usage glucocorticoid, antiinflammatory
usage betamethasone is a glucocorticoid used as an anti-inflammatory agent.
usage anti-inflammatory, immunosuppressive
betamethasone preparation products and raw materials
raw materials betamethasone 21-acetate

hennan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion, the com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others . these products have been being well exported to europe , southeast asia , the middle east , africa , south america and some other countries and areas.

Details

betamethasone basic information
hormone drugs chemical properties application production method category toxicity grading acute toxicityflammability and hazard characteristics storage characteristics extinguishing agent
product name: betamethasone
synonyms: (11beta,16beta)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione;16-beta-methyl-1,4-pregnadiene-9-alpha-fluoro-11-beta,17-alpha,21-triol-3,20;16-beta-methyl-1,4-pregnadiene-9-alpha-fluoro-11-beta,17-alpha,21-triol-3,20-dione;17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-9-alpha-fluoro-11-bet;6beta)-;9-alpha-fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione;9-alpha-fluoro-11-beta,17-alpha,21-trihydroxy-16-beta-methylpregna-1,4-diene;9-alpha-fluoro-16-beta-methyl-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20
cas: 378-44-9
mf: c22h29fo5
mw: 392.46
einecs: 206-825-4
product categories: biochemistry;hydroxyketosteroids;steroids;intermediates & fine chemicals;pharmaceuticals;steroid and hormone;pharmaceutical intermediate;celestone
mol file: 378-44-9.mol
betamethasone structure
betamethasone chemical properties
mp 235-237°c
refractive index 118 ° (c=1, dioxane)
storage temp. 0-6°c
merck 1180
cas database reference 378-44-9(cas database reference)
nist chemistry reference pregna-1,4-diene-3,20-dione, 9alpha-fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl-(378-44-9)
safety information
hazard codes xi,xn,t
risk statements 40-48/20/21-61
safety statements 22-36-45-53
rtecs tu4000000
hs code 29379000
hazardous substances data 378-44-9(hazardous substances data)
msds information
betamethasone usage and synthesis
hormone drugs betamethasone, belongs to adrenal corticosteroids, it is a isomer of dexamethasone , and the role of betamethasone is similiar to prednisolone and dexamethasone , it has anti-inflammatory, anti-rheumatic, anti-allergic and suppression of the immune and other pharmacological effects, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone etc. , it can reduce and prevent tissue response to inflammation and eliminate heat, redness and swelling caused by local non-infectious inflammation, thereby reducing the performance of inflammation, anti-inflammatory effect of this product 0.3mg is equal to dexamethasone 0.75mg, prednisone 5mg or 25mg cortisone .
betamethasone sodium retention effect is a hundred times more than hydrocortisone, in primary adrenal hypofunction, it can be used together with glucocorticoid for replacement therapy ,and it is used for preventing or inhibiting cell-mediated immune response, delaying allergic reactions and reducing the primary immune response expansion ,it is used for low renin and low aldosterone syndrome and autonomic neuropathy induced orthostatic hypotension.
currently betamethasone is also used for the treatment of active rheumatoid arthritis, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, atopic dermatitis, eczema, neurodermatitis, seborrheic dermatitis, and pruritus and comprehensive treatment of certain infections.
the product is contraindicated in severe psychiatric history, active duodenal ulcer, recent gastrointestinal anastomosis, heavier osteoporosis, overt diabetes, severe hypertension, virus , bacterial, fungal infections which are failed to control by the use of antimicrobial agents , thrombophlebitis, skin infections, such as impetigo, tinea, jock itch and so on.
the above information is edited by the chemicalbook of tian ye.
chemical properties white crystalline powder. mp 231-234 deg.] c (decomposition). odorless. acetate betamethasone ([987-24-6]) is also white crystalline powder, melting point 205-208 ℃, slightly soluble in alcohol, ethanol, and very slightly soluble in chloroform or ether, insoluble in water, odorless.
application hormone drugs.it is mainly used for anti-inflammatory and anti-allergic. it is suitable for rheumatoid arthritis and various skin diseases. betamethasone role is similiar to dexamethasone, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone and it has few side effects.
production method according to u.s. patent no. 3,164,618, betamethasone acetate is dealt with hydrochloric acid in methanol - chloroform - water mixture , it can be converted to betamethasone.
category toxic substances
toxicity grading middle toxic
acute toxicity oral -mouse ld50:> 4500 mg / kg
flammability and hazard characteristics combustible;its combustion produces toxic fumes of fluoride.
storage characteristics ventilated, low-temperature ,dry storeroom.
extinguishing agent dry powder , foam, sand, carbon dioxide, water spray.
chemical properties white to off-white solid
usage glucocorticoid, antiinflammatory
usage betamethasone is a glucocorticoid used as an anti-inflammatory agent.
usage anti-inflammatory, immunosuppressive
betamethasone preparation products and raw materials
raw materials betamethasone 21-acetate

hennan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion, the com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others . these products have been being well exported to europe , southeast asia , the middle east , africa , south america and some other countries and areas.

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