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Jinan Jiage biological technology co., LTD99% Puirty pharmaceutical material API Tacrolimus for anti inflamatory//file1.lookchem.com/cas/reactions/2021/05/27/3647477.png
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99% Puirty pharmaceutical material API Tacrolimus for anti inflamatory CAS NO.104987-11-3

FOB Price:
USD 0.50-1.00 /Gram Get Latest Price
Min.Order Quantity:
10 Gram
Purity:
>99%
Port:
shenzhen
Payment Terms:
L/C,T/T,MoneyGram,Other

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Product Details

Keywords

  • raw pharmaceutical material
  • anti inflamatory hormone
  • API

Quick Details

  • ProName: 99% Puirty pharmaceutical material API...
  • CasNo: 104987-11-3
  • Molecular Formula: C44H69NO12
  • Appearance: White powder
  • Application: health & medicine, chemical, pharmaceu...
  • DeliveryTime: 24 hours after your payment
  • PackAge: Discreet packing ways as your requirem...
  • Port: shenzhen
  • ProductionCapacity: 1000 Kilogram/Month
  • Purity: >99%
  • Storage: Discreet packing ways as your requirem...
  • Transportation: As your required
  • LimitNum: 10 Gram
  • CAS NO: 104987-11-3
  • MF: C44H69NO12
  • MW: 804.02
  • Purity: 99.5% min
  • Appearance: White powder
  • Certification: ISO 9001, USP, BP
  • Standard: Enterprise standard
  • Usage: treatment of Cushing's syndrome

Superiority

1. rich experience. our company is a professional production leading factory in china in pharmaceutical
area of many years.
2. discreet package. the packing suits you best would be choosen to cross customs safely. or if you
have your own ideal way, it could be also taken into consideration.
3. top quality. high quality guaranteed, once any problem is found, the package would be reshipped for you .
4. security shipping.shipping by express (fedex,ups,dhl,ems), by air.the most professional
forwarder would be recommanded for you.
5. fast delivery. we have stock, so we can delivery quickly once payment is received.
6. quality service. we will give you warm after-sale service,if any question we will reply you within 24
hours.
7. competitive prices. a discount would be given when you make a large order.

Details

99% puirty pharmaceutical material api tacrolimus for anti inflamatory

synonym

prograf; tsukubaenolide

cas no

104987-11-3

mf

c44h69no12

mw

804.02

purity

99%

appearance

white powder

melting point

113-115° c

certification

iso 9001, usp, sgs

standard

enterprise standard

usage

treatment of cushing's syndrome

packing

discreet packing ways as your requirement, 100% go through.

storage

store in a cool, dry place. do not store in direct sunlight. store in a tightly closed container.

usage:


tacrolimus is used to prevent rejection of organ transplants.

tacrolimus is 10 to 100 times superior to cyclosporin in improving graft survival and preventing acute rejection

after transplantation, but decreasing the toxin side effects.


tacrolimus is an anti-rejection in organ transplantation.

tacrolimus is can treat skin diseases. like atopic dermatitis (ad), systemic lupus erythematosus (sle),autoimmune

eye disease and other autoimmune diseases.

description:


tacrolimus (also fk-506 or fujimycin, trade names prograf, advagraf, protopic) is an immunosuppressive drug

used mainly after allogeneic organ transplant to lower the risk of organ rejection. it achieves this by inhibiting the

production of interleukin-2, a molecule that promotes the development and proliferation of t cells, which are vital

to the body's learned (or adaptive) immune response. tacrolimus is also used in the treatment of other t cell-

mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe

refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, kimura's disease,

and the skin condition vitiligo.

application:


l immunosuppression following transplantation it has similar immunosuppressive properties to ciclosporin, but is

much more potent. immunosuppression with tacrolimus was associated with a significantly lower rate of acute

rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. clinical outcome

is better with tacrolimus than with ciclosporin during the first year of liver transplantation. long term outcome has

not been improved to the same extent. tacrolimus is normally prescribed as part of a post-transplant cocktail

including steroids, mycophenolate and il-2 receptor inhibitors. dosages are titrated to target blood levels.

typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.

coa:

tests

specifications

results

description

a white or off-white crystalline powder

conform

identification

1. ir (usp <197k>)

conform

2. hplc retention times

conform

water (usp <921> method i)

1.6 ~ 3.0%

2.1%

residue on ignition (usp <281>)

<0.2%

0.08%

heavy metals (usp <231> ii)

<20 ppm

<20 ppm

related substances (inhouse hplc method)

ascomycin £ 0.8%

0.064%

residual solvents(inhouse method)

acetone £ 2000 ppm

not detected

assay (on anhydrous basis)

98.0% ~ 102.0%

100.0%

conclusion

complied with in-house standard

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