Buy High quality/lowest price of Dofetilide CAS NO.115256-11-6

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more than a little (115256-11-6) is one of the more specific the first ⅲ anti-arrhythmic drugs, it is to extend the time of action potential and effective refractory period, but does not affect the heart conduction velocity. the mechanism of these effects is that it can inhibit the fast part of the hysteresis outward potassium current, thus blocking the outflow of potassium ions during the repolarization phase. relevant research shows that the drug can treat and prevent atrial arrhythmia, such as atrial fibrillation, atrial flutter and paroxysmal supraventricular tachycardia, but also prevent the occurrence of ventricular tachycardia. it has been shown to reduce the incidence of complications in patients with heart failure. the most serious adverse reaction to dofeirite is the induction of ventricular arrhythmias (especially tip torsive ventricular tachycardia).