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lurasidone hydrochloride basic information |
product name: | lurasidone hydrochloride |
synonyms: | lurasidonhydrochloride;lurasidonhydrochlorid;(3ar,4s,7r,7as)-2-[[(1r,2r)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1h-isoindole-1,3(2h)-dione hydrochloride;(1r,2s,3r,4s)-n-[(1r,2r)-2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl]-1-cyclohexylmethyl]-2,3-bicyclo[2.2.1]heptanedicarboxyimide hydrochloride;latuda, sm 13496;lurasidone hydrochlorid;(3ar,4s,7r,7as)-2-[(1r,2r)-2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-ylmethyl]cyclohexylmethyl]hexahydro-1h-4,7-methanoisoindole-1,3-dione hydrochloride;4,7-methano-1h-isoindole-1,3(2h)-dione, 2-[[(1r,2r)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-, hydrochloride (1:1), (3ar,4s,7r,7as)- |
cas: | 367514-88-3 |
mf: | c28h36n4o2s |
mw: | 492.684 |
einecs: | 200-659-6 |
product categories: | chiral reagents;intermediates & fine chemicals;pharmaceuticals |
mol file: | 367514-88-3.mol |
lurasidone hydrochloride chemical properties |
melting point | 198-205°c |
fp | 9℃ |
storage temp. | refrigerator |
inchikey | pqxkdmsybgkcja-cvtjibdqsa-n |
safety information |
hazard codes | f,t |
risk statements | 11-23/24/25-39/23/24/25 |
safety statements | 7-16-36/37-45 |
ridadr | un1230 - class 3 - pg 2 - methanol, solution |
lurasidone hydrochloride usage and synthesis |
chemical properties | off-white solid |
uses | lurasidone is an atypical antipsychotic, inhibits dopamine d2, 5-ht2a, 5-ht7, 5-ht1a and noradrenaline α2c with ic50 of 1.68 nm, 2.03 nm, 0.495 nm, 6.75 nm and 10.8 nm, respectively |
uses | an antipsychotic used for treatment of schizophrenia. |
definition | chebi: a hydrochloride obtained by reaction of lurasidone with one equivalent of hydrochloric acid. an atypical antipsychotic agent used for the treatment of schizophrenia. |