CAS:123441-03-2 Rivastigmine CAS NO.114899-77-3

Min.Order Quantity:: 1 Kilogram

Purity:: 99.5%

Port:: all chinese port

Payment Terms:: T/T,MoneyGram,Other

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Product Details

Keywords

Rivastigmine
Rivastigmine high purity
3-((1S)-1-(Dimethylamino)ethyl)phenyl N-ethyl-N-methylcarbamate

Quick Details

ProName: CAS:123441-03-2 Rivastigmine
CasNo: 114899-77-3
Molecular Formula: C14H22N2O2
Appearance: White powder
Application: Medicine
DeliveryTime: within 3-4days after received your pay...
PackAge: according to customers' requirements
Port: all chinese port
ProductionCapacity: 100 Kilogram/Week
Purity: 99.5%
Storage: store in cool and dry
Transportation: by sea or by air
LimitNum: 1 Kilogram

Superiority

english name:rivastigmine tartrate

molecular formula : c18h28n2o8

molecular weight : 400.4235

cas: 129101-54-8

synonyms: sdz-ena 713;ena 713;ena-713;rivastigmine hydrogentartrate;unii-9iy2357jpe;carbamic acid, ethylmethyl-, 3-((1s)-1-(dimethylamino)ethyl)phenyl ester, (2r,3r)-2,3-dihydroxybutanedioate (1:1);carbamic acid, ethylmethyl-, 3-(1-(dimethylamino)ethyl)phenyl ester, (s)-, (r-(r*,r*))-2,3-dihydroxybutanedioate (1:1);rivastigmine hydrogen tartrate;3-[(1s)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate 2,3-dihydroxybutanedioate (1:1);3-[(1s)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate 2,3-dihydroxybutanedioate (salt);rivastigimine tartrate;

introduction:

rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the alzheimer's type and dementia due to parkinson's disease. the drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting. the drug is eliminated through the urine, and appears to have relatively few drug-drug interactions.

specification

item	requirements	test results
appearance	white or off-white powder	white powder
identification	nmr,ms	complies
water	≤0.50%	0.4%
melting point	121℃~126℃	122.0℃~124.1℃
specific rotation	+4.0°~+6.0°	+5.9°
related substances(hplc)	conformed
(s)-3-1(-dimethylamino)ethyl-phenol	≤0.30%	0.2%
any other individual impurity:	≤0.50%	0.31%
total impurity	≤1.0%	0.8%
residues on ignition	≤0.1%	0.05%
residual solvent	ethanol≤0.5% acetonitrile≤0.041% dichloromethane≤0.06% ethyl acetate≤0.5%	nd nd nd nd 0.023%
heavy metals	≤10ppm	<10ppm
purity	≥99.0%	99. 9%
conclusion	meets the requirements

application

do not use rivastigmine if:

you are allergic to any ingredient in rivastigmine or to carbamate derivatives (eg, meprobamate)
you have had a skin reaction to the patch form of rivastigmine in the past and you have not had a negative allergy test
you are taking another form of rivastigmine (eg, patch, solution) or another cholinesterase inhibitor (eg, donepezil)
you are taking acebutolol, atenolol, betaxolol, bisoprolol, carvedilol, esmolol, labetalol, metoclopramide, metoprolol, nadolol, nebivolol, penbutolol, pindolol, propranolol, sotalol, or timolol

how to use rivastigmine:

use rivastigmine as directed by your doctor. check the label on the medicine for exact dosing instructions.

take rivastigmine by mouth with the morning and evening meals, unless your doctor tells you otherwise.
take rivastigmine on a regular schedule to get the most benefit from it.
taking rivastigmine at the same time each day will help you remember to take it.
continue to take rivastigmine even if you feel well. do not miss any doses.
if you miss a dose of rivastigmine, take it as soon as possible. if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. do not take 2 doses at once. contact your doctor if you miss several doses of rivastigmine. your doctor may need to restart your medicine at a lower dose to avoid side effects.

packaging & shipping

trabectedin cas: 114899-77-3 // pharmaceutical grade

Details

kono chem co.,ltd is a leading producer of standardized herbal extracts, natural active ingredients and apis for pharmaceutical, health food and cosmetic industries.

the botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by pioneer. they include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis.

with our phytopharmaceutical background and knowledge through experience, pioneer can also provide a wide range of analytical services and reference substances to our clients. in addition, we also manufacture pharmaceutical raw materials of nucleotide species, mainly including as below: sam-e tosylate disulfate; sam-e 1,4-butanedisulfonate; polycytidylic acid; polyinosinic acid; adenosine triphosphate disodium; and cytidine triphosphate disodium; these items are our strongest advantage in china. meanwhile, we can do custom made pharmaceutical ingredients depending on our professional experts in the pharmaceutical and chemistry industry.

recently, kono chem has been working hard on the research and development of new cardiovascular and anesthesia drugs, we have got good achievements; moreover, we also offer natural anticancer drugs and other pharmaceutical intermediates. as a gmp standardized manufacturer, our products can meet or even exceed the standards of cp2010, usp32, bp2005 and ep4. presently, 80% and above of our products have been well-recognized in dozens of countries and regions, such as usa, eu, south america and southeast asia. there are experienced technicians working for our institutes now, all of them are skilled. pioneer is looking forward to cooperating with friends all over the world for getting collaborative development; we are willing to work with you to develop new drugs and expand new business, let's work together for bright future.