USD $1.00-1.00 / Kilogram
USD $10.00-10.00 / Gram
USD $20.00-40.00 / Kilogram
USD $3.00-10.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
combretastatin a-4 basic information |
product name: | combretastatin a-4 |
synonyms: | (z)-2-methoxy-5-(3,4,5-trimethoxystyryl)phenol;(z)-2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenol,3,4,5-trimethoxy-3hydroxy-4methoxy-(z)-stilbene,cs-a4;combrestatin a4( 2-methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol );(z)-2-methoxy-5-(3,4,5-trimethoxystyryl)phenol ,98%;2-methoxy-5-[(z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol;3-[(z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-6-methoxyphenol;5-[(z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-2-methoxyphenol;combretastatin a4 |
cas: | 117048-59-6 |
mf: | c18h20o5 |
mw: | 316.3484 |
einecs: | |
product categories: | inhibitors;combretastatin;anti-cancer & immunity;api |
mol file: | 117048-59-6.mol |
combretastatin a-4 chemical properties |
mp | 84.5-85.5°c |
storage temp. | desiccate at -20°c |
safety information |
hazard codes | t |
risk statements | 23/24/25-41 |
safety statements | 26-36/37-39-45 |
ridadr | un 2811 |
combretastatin a-4 usage and synthesis |
chemical properties | crystalline powder |
usage | combretastatin is a small organic molecule found in the bark of the african bush willow tree combretum caffrum. combretastatin-a4 prodrug induces mitotic catastrophe in chronic lymphocytic leukemia cell line independent of caspase activation and poly(adp-ribose) polymerase cleavage. a potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site. |
biological activity | antitumor, antiangiogenic and antimetastatic agent, in vitro and in vivo . acts by inhibiting tubulin polymerization (ic 50 = 2-3 μ m). |
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