Welcome to LookChem.com Sign In|Join Free
  • or
HENAN SUNLAKE ENTERPRISE CORPORATIONCytarabine 147-94-4 C9H13N3O5//file1.lookchem.com/cas/reactions/2021/05/28/89175.png
qq

Communicate with Supplier:

Ms. summer
Ms. summer: What can I do for you?

Cytarabine 147-94-4 C9H13N3O5 CAS NO.147-94-4

Min.Order Quantity:
1 Kilogram
Purity:
99%
Port:
China main port
Payment Terms:
D/A,D/P,T/T

Add to Inquiry Cart

Product Details

Keywords

  • Cytarabine
  • 147-94-4
  • C9H13N3O5

Quick Details

  • ProName: Cytarabine 147-94-4 C9H13N3O5
  • CasNo: 147-94-4
  • Molecular Formula: C9H13N3O5
  • Appearance: detailed in specifcations
  • Application: Aripiprazole Intermediate functional...
  • DeliveryTime: within 5days
  • PackAge: as needed
  • Port: China main port
  • ProductionCapacity: 500 Metric Ton/Month
  • Purity: 99%
  • Storage: Keep in dry and cool condition
  • Transportation: by air or sea
  • LimitNum: 1 Kilogram
  • MF: C13H21O3PS

Superiority

our services

1.certificate of analysis (coa)

2.material safety data sheet (msds)

3.route of synthesis (ros)

4.method of aanlysis (moa)

5.nuclear magnetic resonance (nmr)

6.packing pictures and loading video before loading

7.free sample

9.factory audit

10.strong after-sale service

company information

henan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion, the com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others . these products have been being well exported to europe , southeast asia , the middle east , africa , south america and some other countries and areas.we sincerely welcome foreign friends to visit our plant for cooperation. with the idea of "quality first,credit priority, excellent service", we are highly acknowledged by customers for good quality and competitive price. more importantly , the company has a strong r & d team, who are professional engineers and scholars with ph. d. .so we are confident to serve you better with our high - quality products and professional team.we are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.we welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.

Details

cytarabine basic information
antiviral drugs anti-tumor drug pharmacokinetics dosing instructions dosage adverse reactions function category toxicity grading acute toxicity stimulus data flammability hazard characteristics storage characteristics extinguishing agent
product name: cytarabine
synonyms: 1-arabinofuranosylcytosine;1-beta-arabinofuranosylcytosine;1-beta-d-arabinofuranosyl-4-amino-2(1h)pyrimidinone;1-beta-d-arabinofuranosyl-cytosin;1-beta-d-arabinosyl-cytosin;1-beta-d-arabinosylcytosine;4-amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin;4-amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine
cas: 147-94-4
mf: c9h13n3o5
mw: 243.22
einecs: 205-705-9
product categories: active pharmaceutical ingredients;api intermediates;antivirals for research and experimental use;biochemistry;chemical reagents for pharmacology research;nucleosides and their analogs;nucleosides, nucleotides & related reagents;bases & related reagents;carbohydrates & derivatives;nucleotides;depocyt;anti-cancer&immunity
mol file: 147-94-4.mol
cytarabine structure
cytarabine chemical properties
mp 214 °c
storage temp. 2-8°c
solubility h2o: 50 mg/ml, clear, colorless
form crystalline
merck 2784
cas database reference 147-94-4(cas database reference)
safety information
hazard codes xn,xi
risk statements 43-63-36/37/38-20/21/22
safety statements 36/37-37/39-36-26
wgk germany 3
rtecs ha5425000
f 10-23
hs code 29349990
hazardous substances data 147-94-4(hazardous substances data)
msds information
cytarabine usage and synthesis
antiviral drugs cytarabine is a kind of purine nucleoside-class antiviral chemical synthesis that initially extracted from the medium of streptomyces, and then produced from chemical synthesis. it is a white crystalline powder and is very slightly soluble in water. its monophosphate ester is easily soluble in water. it has inhibitory effect on various kinds of dna virus such as herpes simplex virus hsv1 and hsv2, hepatitis b virus, varicella-zoster virus and cytomegalovirus however has no effect on the smallpox virus, adenovirus, and other kinds of dna or rna viruses, bacteria and fungi. the exact mechanism of the antiviral effect of cytarabine is currently not fully understood. the mechanism is primarily related to inhibition of viral replication. the drugs and their metabolites can inhibit the viral dna synthesis through inhibiting viral dna polymerase while only a very small amount of the drug itself is incorporated into the viral dna molecule. in the human body, the antiviral effect of the drugs only partially depends on the host immune function with drugs having no immunosuppression effect. upon intravenous administration in vivo, 75% to 87% of the drug quickly deaminized into arabinose hypoxanthine through the action of deadenylated deoxygenase, arabinose hypoxanthine has a significant lower antiviral activity than the prototype, and is rapidly distributed in some parts of the tissues; administer 10 mg of drugs per kg of body weight; the peak value of the plasma concentration of arabinose hypoxanthine is 3 ~ 6μ/ml while the peak value of plasma concentration of vidarabine is 0.2 ~ 0.4μg/ml. arabinose hypoxanthine can penetrate through the blood-brain barrier with the cerebrospinal fluid drug concentrations being approximately 1/3 of plasma drug concentration. 41% to 53% of the daily dosage is excreted through urinary in the form of arabinose hypoxanthine. 1% to 3% is excreted out in the form of prototype. cytarabine is clinically mainly used for the treatment of herpes simplex virus encephalitis as well as being used for treating the herpes zoster and chicken pox of immunosuppressed patients but is invalid in treating cytomegalovirus. it also has certain pharmacological activity of inhibition of hepatitis b virus replication. topical medication is applied to the treatment of herpes simplex virus keratitis and occasionally used for treating vaccinia virus keratitis.
the above information is edited by the chemicalbook of dai xiongfeng.
anti-tumor drug cytarabine is currently one of the most effective drugs in clinical treatment of acute non-lymphatic myeloid leukaemia. it was first successfully synthesized in 1959 f, and is also presented in the sponge. in 1961, it was found that it has inhibitor effect on in mice s180 sarcoma and leukemia l1210. cross resistance phenomenon was not observed in animal experiments for cytarabine being

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)