Diosmin 520-27-4 CAS NO.520-27-4

Min.Order Quantity:: 1 Kilogram

Purity:: 99% min

Port:: Any port of China

Payment Terms:: L/C,T/T,

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Product Details

Keywords

520-27-4
Diosmin
C28H32O15

Quick Details

ProName: Diosmin 520-27-4
CasNo: 520-27-4
Molecular Formula: C28H32O15
Appearance: white powder
Application: industry use
DeliveryTime: with 10 days after order confirmed
PackAge: according to the demand of cusotmer
Port: Any port of China
ProductionCapacity: 1 Metric Ton/Day
Purity: 99% min
Storage: room temperature
Transportation: by air
LimitNum: 1 Kilogram
Grade: Industrial Grade,Food Grade,Pharma Gra...

Superiority

our company was built in 2009 with an iso certificate.in the past 5 years, we have grown up as a famous fine chemicals supplier in china and we had established stable business relationships with samsung,lg,merck,thermo fisher scientific and so on.our main business covers the fields below:

1.noble metal catalysts (pt.pd...)

2.organic phosphine ligands (tert-butyl-phosphine.cyclohexyl-phosphine...)

3.oled intermediates (fluorene,carbazole,boric acid...)

4.customs synthesis

our advantage:

1. higest quality and good package

2.fast delivery

3.better payment term

4.fast response to customer within 6 hours

5.good business credit in europe ,us ,japan ,korea

anyway ,if you need any chemicals from china ,henan tianfu can help you

Details

diosmin basic information

pharmacological effects side effects taboos attentions application pregnant women and nursing mothers drug use

product name:	diosmin
synonyms:	diosmetin-7-o-rutinoside;diosmetin-7-rutinoside;diosmin;barosmin;3',5,7-trihydroxy-4'-methoxyflavone 7-rutinoside;3,5,7-trihydroxy-4-methoxyflavone 7-rutinoside;diosmine ep4;diosmine
cas:	520-27-4
mf:	c28h32o15
mw:	608.54
einecs:	208-289-7
product categories:	tetra-substituted flavones;plant extract;active pharmaceutical ingredients;aromatics;intermediates & fine chemicals;oligosaccharides;pharmaceuticals;plant extracts;herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from chinese medicinal herbs (tcm).;standardized herbal extract;diosmil;inhibitors
mol file:	520-27-4.mol

diosmin chemical properties

mp	277-278°c
storage temp.	2-8°c
merck	13,3327
cas database reference	520-27-4(cas database reference)

safety information

hazard codes	xi
risk statements	36/37/38
safety statements	26-36-36/37
wgk germany	3

msds information

provider	language
sigmaaldrich	english

diosmin usage and synthesis

pharmacological effects	diosmin is also called alvenor. it is a kind of drug for the treatment of hemorrhoid symptoms related to acute episodes, can also be used in the treatment of symptoms associated with venous lymphatic insufficiency (leg heavy, pain, morning acid swells discomfort). the effects of diosmin are as below: 1, has specific affinity to the venous system, enhance the tension system without affecting the artery of vein; 2, to the microcirculation system, decrease the blood viscosity, improve the velocity of reducing silt up; 3, contract the lymphatic system, which can enhance lymphatic and lymph drainage speed, speed up the return relieve edema. 4, commercially available diosmin uses micronization technology, increase the contact area after using medicine, absorb more and higher bioavailability. suitable for all kinds of hemorrhoids and acute hemorrhoids, also can be used for the treatment of chronic venous insufficiency, such as varicose veins, leg ulcers, etc. this information is edited by chemicalbook xiao nan.
side effects	1, may appear nausea, vomiting, abdominal pain, dyspepsia, diarrhea, insomnia, dizziness, headache, drowsiness, anxiety and other adverse reactions. 2, there may be a few of minor gastrointestinal reactions and adverse reactions such as plant nerve function disorder, but generally mild and don't have to stop the drug. 3, pregnant women and nursing mothers with hemorrhoids are safe to use this product.
taboos	people who allergy to any ingredients in this product are prohibited.
attentions	hemorrhoid acute episodes: treatment with this drug can't replace any other special treatments needed for handling anus diseases. this treatment must be short. if symptoms cannot eliminate quickly, anorectal epidemiology check and review should be needed. this product contains flavonoids which is the effective composition of glycosides in plants. effective flavonoid content for each piece of diosmin is 450 mg, 50 mg of hesperidin, the total flavonoid glycosides composition (also called daflon) is 500 mg. general flavonoids have certain biological activity, but low toxicity and rare allergic reactions, if any allergies, stop the drug.
application	used in food, medicine, health products, etc action mechanism: 1.enhance the vein tension, even not exceptional under high temperature condition. it has a stronger effect causing the constriction of vein than other drugs such as rutin, still can enhance the tension of the vein when the body was acidosis. diosmin has specific affinity for vein without affecting the arterial system. 2. improve microcirculation. diosmin can obviously reduce the white blood cells and vascular endothelial cell adhesion, migration, disintegrating the release of inflammatory substances, such as histamine, slow excitation peptide, complement, leukotriene, prostaglandins, and too many free radicals, reducing the permeability of capillaries and enhance its tension. diosmin can lower blood viscosity, enhance the function of red blood cell velocity, thus reduce the microcirculation clogged. 3. promote lymphatic circumfluence. diosmin can increase the speed of lymphatic drainage.
pregnant women and nursing mothers drug use	pregnancy women use: animal experiments did not show any teratogenic effects. so far, still no harmful reports to human. delivery: there is no detailed research data. nursing mothers use: although there is no information on drug secreted with breast milk, but treatment is not recommended during breastfeeding.
chemical properties	brown powder
usage	vascular protectant
usage	naturally occurring flavonic glycoside; rhamnoglycoside of diosmetin. capillary protectant