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Jinan Hongfangde Pharmatech Co.,LtdDonepezil hydrochloride//www.lookchem.com/300w/2010/0625/120011-70-3.jpg
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Donepezil hydrochloride CAS NO.120011-70-3

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FOB Price:
USD 1.00-1.00 /Kilogram Get Latest Price
Min.Order Quantity:
1 Kilogram
Purity:
99.0%
Port:
china（qingdao/beijing/shanghai/hangzhou/shenzheng
Payment Terms:
T/T,MoneyGram,Other

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Product Details

Keywords

  • Donepezil hydrochloride cas:120011-70-3
  • Donepezil hcl
  • Donepezil HCL

Quick Details

  • ProName: Donepezil hydrochloride
  • CasNo: 120011-70-3
  • Molecular Formula: C24H30ClNO3
  • Appearance: powder
  • Application: cas:120011-70-3 Pharmaceutical interm...
  • DeliveryTime: According to the contract requirements
  • PackAge: fiber can/aluminum foil bag
  • Port: china（qingdao/beijing/shanghai/hangzho...
  • ProductionCapacity: 75 Kilogram/Month
  • Purity: 99.0%
  • Storage: 20-25℃
  • Transportation: by air/by sea
  • LimitNum: 1 Kilogram
  • Moisture Content: 0.1
  • Impurity: 0.03%
  • Grade: Pharma Grade
  • assay: 99%
  • Standard: EP9, USP40
  • Sodium chloride: 0.1%

Superiority

donepezil, marketed under the trade name aricept by its developereisai and partner pfizer, and also marketed under the brand name donepby alkem pentacare, is a centrally acting reversibleacetylcholinesterase inhibitor.[1] its main therapeutic use is in thepalliative treatment of alzheimer's disease.[2] common side effects include gastrointestinal upset. it has an oral bioavailability of 100% and easily crosses the blood–brain barrier. because it has a biological half-life of about 70 hours, it can be taken once a day.

Details

donepezil
systematic (iupac) name
(rs)-2-[(1-benzyl-4-piperidyl)methyl]- 5,6-dimethoxy-2,3-dihydroinden-1-one
clinical data
trade names aricept
ahfs/drugs.com monograph
medlineplus a697032
pregnancy cat. c
legal status prescription only
routes oral tablet, 5,10 & 23mg
pharmacokinetic data
bioavailability 100 (%)
protein binding 96%
half-life 70 hours
excretion 0,11-0,13 (l/h/kg)
identifiers
cas number 120014-06-4 yes
atc code n06da02
pubchem cid 3152
drugbank db00843
chemspider 3040 yes
unii 8ssc91326p yes
kegg d07869 yes
chebi chebi:53289 yes
chembl chembl502 yes
chemical data
formula c24h29no3
mol. mass 379.492 g/mol

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