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Henan Allgreen Chemical Co.,LtdGefitinib//file1.lookchem.com/cas/reactions/2021/05/26/8949523.png

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Gefitinib CAS NO.184475-35-2

Min.Order Quantity:
1 Kilogram
Purity:
98%
Port:
shanghai
Payment Terms:
L/C,D/A,D/P,T/T,

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Product Details

Keywords

  • 184475-35-2
  • Gefitinib
  • C22H24ClFN4O3

Quick Details

  • ProName: Gefitinib
  • CasNo: 184475-35-2
  • Molecular Formula: C22H24ClFN4O3
  • Appearance: White or off-white Solid
  • Application: Organic synthesis
  • DeliveryTime: 20day
  • PackAge: According to the demand of customer
  • Port: shanghai
  • ProductionCapacity: 20 Metric Ton/Month
  • Purity: 98%
  • Storage: Sealed, dry, microtherm , avoid light ...
  • Transportation: by air or by sea
  • LimitNum: 1 Kilogram
  • Grade: Industrial Grade,Pharma Grade,Electron...

Superiority

high quality

Details

gefitinib basic information
product name: gefitinib
synonyms: iressa;gefitinib;akos 91371;n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;n-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine;zd 1839;4-quinazolinamine, n-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-;gefitinib(tinibs)
cas: 184475-35-2
mf: c22h24clfn4o3
mw: 446.9
einecs:
product categories: active pharmaceutical ingredients;gefitinib;molecular targeted antineoplastic;intermediates & fine chemicals;pharmaceuticals;pharmaceutical intermediate;apis;iressa;anti-cancer&immunity;api
mol file: 184475-35-2.mol
gefitinib structure
gefitinib chemical properties
mp 119-1200c
storage temp. store at rt
cas database reference 184475-35-2(cas database reference)
safety information
msds information
gefitinib usage and synthesis
chemical properties light-yellow crystalline powder
usage gefitinib (iressa, zd-1839) is an egfr inhibitor for tyr1173, tyr992, tyr1173 and tyr992 in the nr6wtegfr and nr6w cells with ic50 of 37 nm, 37nm, 26 nm and 57 nm, respectively.
usage gefitinib is an antineoplastic.
biological activity orally active, selective inhibitor of egfr tyrosine kinase (ic 50 = 23-79 nm). shows minimal activity against erbb2, kdr, c-flt, pkc, mek and erk-2. blocks egfr autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts.
gefitinib preparation products and raw materials

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