High purity antineoplastic agent Capecitabine with best quality CAS NO.154361-50-9

product name:

capecitabine

synonyms:

5'-deoxy-5-fluorocytisine;5'-deoxy-5-fluoro-n-[(pentyloxy)carbonyl]cytidine;capecitabine;ro-9-1978;pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate;xeloda;cpecitabine;5deoxy-5-fluoro-n-[(pentyloxy)carbonyl]cytidine, ro-9-1978, xeloda

cas:

154361-50-9

mf:

c15h22fn3o6

mw:

359.35

product categories:

active pharmaceutical ingredients;antineoplastic;bases & related reagents;intermediates & fine chemicals;nucleotides;pharmaceuticals;antineoplastic drug, 5-fu analog;anti-cancer;api;xeloda;cardiovascular drugs;inhibitors

mol file:

154361-50-9.mol

chemical properties

melting point

110-121°c

density

1.49 g/cm3

storage temp.

-20°c freezer

water

≤ 0.3%

specific rotation

+96.0 ~+100.0

usage and synthesis

interactions

no clinical side effect has been seen when it is used in combination with drugs such as antihistamines, nsaids, morphine, acetaminophen, aspirin, anti-nausea drugs, h2 receptor antagonist etc.
the serum protein binding of capecitabine is relatively low (64%); the possibility of binding with drugs that bind tightly to protein through replacement is still unpredictable.
interaction with cytochrome p450 emsyme: no influence of capecitabine on human liver microsome p450 enzyme is found in vitro.
the dose may need to be reduced when any drug among phenytoin and coumarin derivative-type anticoagulants is used in combination with rhoda.

chemical properties

colourless solid

usage

an antineoplastic agent. a prodrug of doxifluridine.

capecitabine is an antineoplastic agent. capecitabine is a prodrug of doxifluridine (d556750).

an antiproliferative 5-fluorouracil releasing compound