iodixanol properties
melting point 262-267 ° c (dec.)
the density is 1.266 ± 0.003
refractive index n 1.4128 ± 0.0003
storage conditions
application and synthesis of iodixanol
chemical properties of melting point 240 ~ 250 ℃. dissolved in water. viscosity (37 ° c) 11.1 mpa · s; ph 7.2 ~ 7.6 (c = 320mgi / m1). 50% aqueous solution (w / v): viscosity 8.3 mpa · s; n1.4128 ± 0.0003; d1.266 ± 0.003. acute toxicity ld50 mice (mg / kg): 21 intravenous injection.
use non-ionic x-ray photographic agent.
use x-ray contrast agent. for cardiovascular angiography in adults, cerebral angiography (conventional with i.a. dsa), peripheral arteriography (conventional with i.a. dsa), abdominal angiography (i.a. dsa), urography, venography, and ct-enhancement.
production method compound (i) and 1,3-dichloro-2-propanol condensation, that iodixanol.