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HENAN SUNLAKE ENTERPRISE CORPORATIONLORCASERIN 616202-92-7 C11H14ClN//file1.lookchem.com/300w/synthetic/2022-01-22-07/f10eb417-0d28-418b-b57a-93238136286e.png
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LORCASERIN 616202-92-7 C11H14ClN CAS NO.616202-92-7

Min.Order Quantity:
1 Kilogram
Purity:
99%
Port:
China main port
Payment Terms:
D/A,D/P,T/T

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Product Details

Keywords

  • LORCASERIN
  • 616202-92-7
  • C11H14ClN

Quick Details

  • ProName: LORCASERIN 616202-92-7 C11H14ClN
  • CasNo: 616202-92-7
  • Molecular Formula: C11H14ClN
  • Appearance: detailed in specifcations
  • Application: Aripiprazole Intermediate functional...
  • DeliveryTime: within 5days
  • PackAge: as needed
  • Port: China main port
  • ProductionCapacity: 500 Metric Ton/Month
  • Purity: 99%
  • Storage: Keep in dry and cool condition
  • Transportation: by air or sea
  • LimitNum: 1 Kilogram
  • MF: C13H21O3PS

Superiority

our services

1.certificate of analysis (coa)

2.material safety data sheet (msds)

3.route of synthesis (ros)

4.method of aanlysis (moa)

5.nuclear magnetic resonance (nmr)

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10.strong after-sale service

company information

henan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion, the com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others . these products have been being well exported to europe , southeast asia , the middle east , africa , south america and some other countries and areas.we sincerely welcome foreign friends to visit our plant for cooperation. with the idea of "quality first,credit priority, excellent service", we are highly acknowledged by customers for good quality and competitive price. more importantly , the company has a strong r & d team, who are professional engineers and scholars with ph. d. .so we are confident to serve you better with our high - quality products and professional team.we are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.we welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.

Details

lorcaserin basic information
weight loss drugs drug interactions safety application
product name: lorcaserin
synonyms: lorcaserin;(r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine;apd 356;apd356;apd-356;ar-10a;unii-637e494o0z;(1r)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1h-3-benzazepine
cas: 616202-92-7
mf: c11h14cln
mw: 195.692
einecs:
product categories: amines;aromatics;chiral reagents;heterocycles;intermediates & fine chemicals;pharmaceuticals
mol file: 616202-92-7.mol
lorcaserin structure
lorcaserin chemical properties
bp 288 ºc
density 1.075
fp 128 ºc
storage temp. -20 c freezer
safety information
msds information
lorcaserin usage and synthesis
weight loss drugs lorcaserin is a new drug for the treatment of obesity , belonging to oral potent selective serotonin 2c receptor agonists, lorcaserin hydrochloride is successfully developed by the us company arena, on june 27, 2012 by the us fda it is approved for marketing, as adjuvant therapy for obesity or merge with at least one weight-related complications in overweight adults in low-calorie diet and exercise basis . clinical studies show that the drug can reduce weight of obesity and overweight patients ,it can improve obesity-related metabolic parameters, and it is well tolerated. lorcaserin affinity for the 5-ht2c 100 times higher than the 5-ht2b (valvular heart disease risk) ,it has good safety,it is the first fda-approved weight-loss drug after 1999 . in a year of lorcaserin treatment, the average weight loss ranges from 3 to 3.7 percent.
drug interactions due to the theoretical possibility of the mechanism of lorcaserin and serotonin syndrome, when lorcaserin is used in combination with the serotonergic neurotransmitter system drugs, extreme caution should be paid, including triptans monoamine oxidase inhibitor agent selective serotonin reuptake inhibitor selective serotonin and norepinephrine reuptake inhibitors, tricyclic antidepressants bupropion dextromethorphan, lithium tramadol and st. john's wort , etc. in addition, when the present product with cyp2d6 substrates when combined with the need to be cautious, because the product can increase the exposure of these drugs.
the above information is edited by the chemicalbook of tian ye.
safety lorcaserin has good tolerability and safety, lorcaserin is used in non-diabetic patients, the most common adverse reactions are headache, dizziness, fatigue, nausea, dry mouth and constipation. this product is used in patients with diabetes, common adverse reactions are headache, back pain, cough, low blood sugar and fatigue.studies have found that lorcaserin and placebo are similar in the proportion of serious adverse reactions, lorcaserin does not increase the incidence of valvular heart disease. after lorcaserin treatment , the incidence of depression is lower , the research shows that the proportion of depression led by lorcaserin 10mgbid, 10mgqd and placebo are 1.9%, 1.1% and 1.8%, emotional low incidence rates are 0.6%, 0.9% and 0.9%, the proportion of suicidal thoughts are 0.9%, 0.6% and 0.7% .the product is pregnancy x-class , pregnant women are disabled; whether this product is secreted by milk is unknown, breast-feeding women need to weigh on the use of the drug; this product is not recommended for children.
application diet pills
chemical properties yellow oil
usage a novel selective 5-ht2c-receptor

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