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Naproxen CAS NO.22204-53-1

Min.Order Quantity:
1 Kilogram
Purity:
98%
Port:
China Main Ports
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

  • Naproxen
  • 22204-53-1
  • manufacturer , better price with good quality

Quick Details

  • ProName: Naproxen
  • CasNo: 22204-53-1
  • Molecular Formula: C14H14O3
  • Appearance: White to light yellow crystal powder
  • Application: Pharmaceuticals
  • DeliveryTime: Within 7 days
  • PackAge: Depended
  • Port: China Main Ports
  • ProductionCapacity: 300 Kilogram/Month
  • Purity: 98%
  • Storage: KEEP COLD
  • Transportation: BY SEA OR AIR
  • LimitNum: 1 Kilogram

Superiority


preview
cbnumber: cb8274937
chemical name: naproxen
molecular formula: c14h14o3
formula weight: 230.26
cas no.: 22204-53-1
naproxen basic information
non-steroidal anti-inflammatory drugs chemical properties application production method category toxicity grading acute toxicity flammability and hazard characteristics storage characteristics extinguishing agent
product name: naproxen
synonyms: ()-2-(methoxy-2-naphthyl)-propionicacid;()-2-(methoxy-2-naphthyl)-propionsaeure;()-propionicaci;(+)-2-(methoxy-2-naphthyl)-propionic acid;(+)-2-(methoxy-2-naphthyl)-propionicacid;(+)-2-(methoxy-2-naphthyl)-propionsaeure;(+)-2-naphthaleneaceticaci;(+)-6-methoxy-alpha-methyl-2-napthaleneacetic acid
cas: 22204-53-1
mf: c14h14o3
mw: 230.26
einecs: 244-838-7
product categories: chiral;carboxylic acids (chiral);chiral building blocks;for resolution of bases;optical resolution;synthetic organic chemistry;intermediates & fine chemicals;pharmaceuticals;lipid signaling;aromatics;aleve;other apis
mol file: 22204-53-1.mol
naproxen structure
naproxen chemical properties
mp 152-154 °c(lit.)
refractive index 67.5 ° (c=1, chcl3)
storage temp. -20°c freezer
merck 14,6417
brn 3591067
cas database reference 22204-53-1(cas database reference)
nist chemistry reference naproxen(22204-53-1)
safety information
hazard codes xn,t,f
risk statements 22-39/23/24/25-23/24/25-11
safety statements 36/37-45-16-7
ridadr un 2811 6.1/pg 3
wgk germany 3
rtecs uf5275000
hazardclass 6.1(b)
packinggroup iii
hazardous substances data 22204-53-1(hazardous substances data)
msds information
provider language
(+)-2-(6-methoxy-2-naphthyl)-propionic acid english
sigmaaldrich english
alfa english
naproxen usage and synthesis
non-steroidal anti-inflammatory drugs naproxen is a non-steroidal anti-inflammatory drug ,it is a pg synthase inhibitor, which can inhibit prostaglandin synthetase, it has significant analgesic and antipyretic effects, oral absorption is rapid and complete, 2 to 4 hours after a dose ,plasma concentration reaches the peak, in the blood , more than 99% is bound to plasma proteins, t1 / 2 is 13 to 14 hours, about 95% is discharged from the urine with the prototype and metabolites.it is clinically used for the treatment of rheumatic and rheumatoid arthritis , osteoarthritis, ankylosing spondylitis, gout, arthritis, tenosynovitis.it can also be used to alleviate pain caused by musculoskeletal sprains, contusions,damages and dysmenorrhea . but it should be noted that like other non-steroidal anti-inflammatory drugs, the same serious gastrointestinal adverse reactions could occur at any time while taking naproxen during treatment, so the active gastroduodenal ulcer patients are hanged, other gastrointestinal tract disease patients should take this drug under close medical supervision.
the above information is edited by the chemicalbook of tian ye.
chemical properties white crystal or crystalline powder. melting point 155.3 ℃. soluble in acetone, soluble in methanol, ethanol, acetic acid, insoluble in benzene, practically insoluble in water. in case of light,it is color-graded, odorless, tasteless.
application it is a non-steroidal anti-inflammatory drug for the relief of fever and inflammation and pain associated with arthritis or other symptoms , it has anti-inflammatory, antipyretic and analgesic effects. naproxen plays a role by inhibiting the cyclooxygenase, which generates prostaglandin and is one kind of enzymes related to inflammatory mediators . it is recommended to take the drug during meals to reduce stomach irritation.
production method by methylation, acetylation with 2-naphthol , 6-methoxy-2-acetonaphthone is produced, then it is condensed with acid ester, then generate the product through isomerization, hydrolysis, oxidation, and split and other reactions.
category toxic substances
toxicity grading highly toxic
acute toxicity oral - rat ld50 248 mg / kg; oral - mouse ld50: 360 mg / kg
flammability and hazard characteristics combustible; combustion produces toxic and acrid smoke.
storage characteristics ventilated, low-temperature ,dry storeroom, it should be stored and transported from food raw materials separately.
extinguishing agent water, dry powder, foam,sand
chemical properties white to light yellow crystal powde
usage an anti-inflammatory, analgesic, antipyretic. a non-steroidal anti-inflammatory
naproxen preparation products and raw materials
raw materials methanol-->toluene-->hydrogen-->2-naphthol-->2-acetyl-6-methoxynaphthalene
preparation products naproxen sodium

Details

henan sunlake enterprise corporation is located in henan province, the central plain of china , which enjoys favorable geogeaphical position and convenient transportion. the comany was established in june 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others . these products have been being well exported to europe , southeast asia , the middle east , africa , south america and some other countries and areas.
we sincerely welcome foreign friends to visit our plant for cooperation. with the idea of "quality first,credit priority, excellent service", we are highly acknowledged by customers for good quality and competitive price. more importantly , the company has a strong r & d team who are professional engineers and scholars with ph. d. .so we are confident to serve you better with our high - quality products and professional team.
we are taking great efforts to provide our customers with demanded goods and professional services, continuously improve our core ability of competition and get the momentum for sustainable development ,which finally makes us being a reliable and professional supplier in international market.
we welcome any inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!
our advantages:
i). we have abundant professional production experience.
ii). we have our own chemical factory.
iii). sample is free of charge.
iv). reasonable price, excellent quality & attentive service
v). prompt reply: we can reply your inquiry and email within 24 hours.
vi). fast delivery: the delivery time is about 10-20 days after receiving the deposit.
vii). we have passed the lfgb, sgs, stc, hsl and some other tests.
viii). we have a unity cooperation team.
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