d(-)-4-hydroxyphenylglycine basic information
product name: d(-)-4-hydroxyphenylglycine
synonyms: d-(-)-2-(4-hydroxyphenyl)glycine;d(-)-2-(p-hydroxyphenyl)glycine;d-(-)-a-4-hydroxyphenylglycine;d-4-hydroxyphenylglicyne;d-(-)-4-hydroxyphenylglycine;d-4-hydroxyphenylglycine;d-alpha-para-hydroxyphenylglycine;(d)-(-)-alfa-4-hydroxyphenyl glycine
cas: 22818-40-2
mf: c8h9no3
mw: 167.16
einecs: 245-247-7
product categories: pharmaceutical intermediates;amino acids series;miscellaneous biochemicals;cephalosporins;peptide synthesis;phenylglycine derivatives;unnatural amino acid derivatives;antidote / antibiotic / antimicrobial
mol file: 22818-40-2.mol
d(-)-4-hydroxyphenylglycine structure
d(-)-4-hydroxyphenylglycine chemical properties
melting point 240 °c (dec.)(lit.)
alpha -156 º (c=1, 1 n hcl)
density 1.396
refractive index -158 ° (c=1, 1mol/l hcl)
storage temp. store below +30°c.
solubility 5g/l
form liquid
color clear colorless to yellow
water solubility 5 g/l (20 ºc)
brn 2210998
cas database reference 22818-40-2(cas database reference)
epa substance registry system benzeneacetic acid, .alpha.-amino-4-hydroxy-, (.alpha.r)-(22818-40-2)
safety information
hazard codes xi
risk statements 36/37/38
safety statements 26-36-24/25
wgk germany 3
tsca yes
hs code 29225000
msds information
provider language
(r)-alpha-amino-4-hydroxybenzeneacetic acid english
acros english
sigmaaldrich english
alfa english
d(-)-4-hydroxyphenylglycine usage and synthesis
chemical properties off-white powder
uses 4-hydroxy-d-(-)-2-phenylglycine is an compound used mainly for the synthetic preparation of β-lactam antibiotics.
definition chebi: the d-enantiomer of 4-hydroxyphenylglycine. a non-proteinogenic amino acid found in herpetosiphon aurantiacus.
d(-)-4-hydroxyphenylglycine preparation products and raw materials
preparation products (2r)-2-[(4-ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid-->d-(-)-a-4-hydroxyphenylglycine dane salt methyl potassium
raw materials phenol-->glyoxal-->glyoxylic acid-->anisic aldehyde-->d(-)-tartaric acid-->dl-tartaric acid-->dl-p-hydroxyphenylglycine