TIANFU-CHEM - NO-ASPIRIN 1 CAS NO.175033-36-0

no-aspirin 1 basic information
product name: no-aspirin 1
synonyms: 2-(acetyloxy)-3-[(nitrooxy)methyl]phenyl ester, benzoic acid;ncx 4016;no-aspirin 1;2-acetyloxybenzoicacid3-nitrooxymethylphenylester;nitroaspirin;2-acetoxybenzoate-2-(1-nitroxymethyl)phenyl ester;c102148;nitric oxide-releasing aspirin
cas: 175033-36-0
mf: c16h13no7
mw: 331.28
einecs:
product categories: aromatics compounds;aromatics;inhibitors;nitric oxide reagents;intermediates & fine chemicals;pharmaceuticals
mol file: 175033-36-0.mol
no-aspirin 1 structure
no-aspirin 1 chemical properties
melting point 61-62°c
storage temp. -20°c freezer
safety information
msds information
no-aspirin 1 usage and synthesis
chemical properties off-white solid
uses no-aspirin 1 is a hybrid molecule of aspirin and a nitric oxide (no) donor. it contains an ester linkage, that when cleaved by esterases in the gut, liver, and plasma releases salicylate and an no-releasing moiety. it also prevents restinosiis, inhibits proliferation of vascular smooth muscle cells, reduces infarct ssize following cardiac ischemia, and exhibits strong chemopreventative effects against colon cancer development.