product name: stavudine
synonyms: stavudine;zerit;3'-deoxythymidin-2'-ene;3'-deoxy-2',3'-didehydrothymidine;1-((2r,5s)-5-hydroxymethyl-2,5-dihydro-furan-2-yl)-5-methyl-1h-pyrimidine-2,4-dione;1-[2,3-dideoxy-beta-d-glycero-pent-2-enofuranosyl]thymine;2',3'-didehydro-3'-deoxythymidine;2',3'-dihydro-2',3'-deoxythymidine
cas: 3056-17-5
mf: c10h12n2o4
mw: 224.21
einecs:
product categories: active pharmaceutical ingredients;chiral;antivirals for research and experimental use;biochemistry;chemical reagents for pharmacology research;nucleosides and their analogs;nucleosides, nucleotides & related reagents;bases & related reagents;nucleotides;pharmaceuticals;api's;hiv/aids/related products;api;atacand;other apis
mol file: 3056-17-5.mol
stavudine structure
stavudine chemical properties
melting point 159-160°c
alpha d25 -39.4° (c = 0.701 in water); d20 -46.1° (c = 0.7 in water)
refractive index -46 ° (c=0.69, h2o)
storage temp. −20°c
water solubility 5-10 g/100 ml at 21 ºc
stability: stable. combustible. incompatible with strong oxidizing agents.
cas database reference 3056-17-5(cas database reference)
epa substance registry system thymidine, 2',3'-didehydro- 3'-deoxy-(3056-17-5)
safety information
hazard codes xi
risk statements 36/37/38
safety statements 26-36
wgk germany 2
rtecs xp2075000
hazardous substances data 3056-17-5(hazardous substances data)
msds information
provider language
3'-deoxy-2',3'-didehydrothymidine english
sigmaaldrich english
stavudine usage and synthesis
chemical properties colourless solid
uses angiotensin 1 receptor antagonist
uses used as an antiviral. a reverse transcriptase inhibitor
definition chebi: a nucleoside analogue obtained by formal dehydration across positions 2 and 3 of thymidine. an inhibitor of hiv-1 reverse transcriptase
general description white crystalline solid or powder. odorless.
air & water reactions water soluble.
reactivity profile stavudine is sensitive to heat. incompatible with strong oxidizing agents .
fire hazard literature sources indicate that stavudine is combustible.