TIANFUCHEM--96036-03-2--High purity Meropenem factory price CAS NO.96036-03-2

meropenem

english synonyms: (4r, 5s, 6s) -3 - [[(3s, 5s) -5-dimethylcarbamoylpyrrolidin-3- ) -pyrrolidin-3-yl] thio] -6 - [(1r) -1-hydroxyethyl] -4-methyl-7- oxo-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid -3-pyrrolidinyl thio) 5-beta, 6-beta (4 *) r *))) - ph; antibioticsm7338; ici194660; meropenem, usp standard; meropenam

cas number: 96036-03-2

molecular formula: c17h25n3o5s

molecular weight: 383.46

einecs number:

related categories: antibiotics; active pharmaceutical ingredients; antibacterial; cnbio; pharmaceutical intermediates; intermediates; arava; other antibiotics; pharmaceutical ingredients; small molecule inhibitors

mol file: 96036-03-2.mol

meropenem

meropenem nature

cas database 96036-03-2 (cas database reference)

meropenem uses and methods of synthesis

semi-synthetic carbapenem antibiotics meropenem is another semi-synthetic carbapenem administered parenterally after imipenem-cilastatin is marketed in the united states. through its covalent bonds with the penicillin-binding proteins (pbps) involved in cell wall synthesis to inhibit bacterial cell wall synthesis, thus playing an antibacterial effect. gram-positive bacteria, gram-negative bacteria are sensitive, especially against gram-negative bacteria have strong antibacterial activity. for example, the minimum inhibitory concentration (mic) of about 90% of enterobacter is 0.08-0.15 mg / l, and more than 90% of pseudomonas aeruginosa strains are highly sensitive to it (mic <4 mg / l) including ampicillin-resistant strains are highly sensitive to them (mic of 0.06-1mg / l). neisseria gonorrhoeae is also highly sensitive to meropenem, its activity is 15 times stronger than imipenem. staphylococcus epidermidis, staphylococcus saprophyticus and other coagulase-negative staphylococci are sensitive to meropenem, and most strains of enterococcus faecalis are highly or moderately sensitive to meropenem. meropenem with a mic of 0.06-4 mg / l inhibits almost all bacteroides fragilis. anaerobic bacteria such as peptostreptococcus, propionibacterium, actinomycetes, etc. are also sensitive to meropenem.