Tianfu Chem Eptifibatide CAS NO.148031-34-9

product name: eptifibatide
synonyms: integrelin;eptifibatide acetate;map-lys-gly-asp-trp-pro-cys-nh2;mpr-harg-gly-asp-trp-pro-cys-nh2,( disulfide bridge:1-7);eptifibatide;human eptifibatide;eptifitide;mpr-harg-gly-asp-trp-pro-cys-nh2,( disulfide bridg on mpr and cys)
cas: 148031-34-9
mf: c35h49n11o9s2
mw: 831.96
einecs: 1533716-785-6
product categories: amino acid derivatives;peptide;proteins
mol file: 148031-34-9.mol
eptifibatide structure
eptifibatide chemical properties
cas database reference 148031-34-9(cas database reference)
safety information
msds information
eptifibatide usage and synthesis
pharmacological effects eptifibatide is a platelet glycoprotein ⅱb/ⅲa receptor reversible antagonist,adverse reactions are mild , it can be discontinued immediately while adverse reactions occur . it has strong effect and high selectivity . it has no antigenicity,and it does not cause allergic reactions. it is used for acute coronary syndrome, coronary intervention before treatment and acute q-wave myocardial infarction. it can relieve unstable angina symptoms and reduce the incidence of cardiovascular events. it can limit the non-q-wave myocardial infarction,and reduce through wall myocardial infarction occurrance.
eptifibatide is used to treat acute coronary syndrome, the starting amount is 180μg/kg, the intravenous maintenance dose is per minute 2μg/kg continuous intravenous infusion 72h, if implementing the primary percutaneous coronary intervention, continuous intravenous drip after surgery is 18~24h. for percutaneous coronary intervention, the starting amount is 180μg/kg intravenous injection, after 2μg/kg continuous intravenous infusion every minute, after 10 min, administrated again with 180μg/kg intravenously per minute , thereafter 2μg/kg continuous intravenous infusion for 18~24h.