2-Deoxy-D-glucose, CAS No. 154-17-6, is an apoptosis inhibitor that has been shown to be taken up by glial cells incubated with insulin. Studies indicate that this compound has the potential to suppress hypoxia in murine retinal tissue. Additionally, 2-Deoxy-D-glucose has been noted to be a glycolytic inhibitor via indirect inhibition of HXK (hexokinase) which results in endoplasmic reticulum stress. Other experiments suggest that this agent upregulates autophagy and lowers ATP levels in certain cancer cell lines.