Endothelin and SARAFOTOXIN S6B (cas 116303-65-2) have similar vasoconstrictor effects and postsynaptically mediated mechanisms
-
Add time:08/03/2019 Source:sciencedirect.com
In the isolated perfused mesenteric vascular bed, porcine endothelin (ET) and SARAFOTOXIN S6B (cas 116303-65-2) produced direct vasoconstriction and potentiated nerve stimulation-induced vasoconstriction. ET also enhanced the vasoconstrictor response to exogenous norepinephrine (NE). Basal or stimulated endogenous NE release was not affected either by ET or sarafotoxin S6b. Qualitatively similar responses to ET and sarafotoxin S6b were always observed, although, in many cases, the response to ET was greater and longer lasting than to sarafotoxin S6b. These results indicate that vasoconstrictor responses to ET or sarafotoxin S6b are mediated primarily by postsynaptic mechanisms. No initial vasodilator response to ET or sarafotoxin S6b was observed in this mesenteric vascular preparation.
We also recommend Trading Suppliers and Manufacturers of SARAFOTOXIN S6B (cas 116303-65-2). Pls Click Website Link as below: cas 116303-65-2 suppliers
Prev:Atypical receptors mediate the response to endothelin-1 and SARAFOTOXIN S6B (cas 116303-65-2) in the human umbilical artery
Next:Cerebellar neurons and glia respond differentially to endothelins and SARAFOTOXIN S6B (cas 116303-65-2)) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- The endothelin peptides ET-1, ET-2, ET-3 and SARAFOTOXIN S6B (cas 116303-65-2) are co-mitogenic with platelet-derived growth factor for vascular smooth muscle cells08/11/2019
- Further studies on the response of the guinea-pig isolated bronchus to endothelins and SARAFOTOXIN S6B (cas 116303-65-2)08/10/2019
- Structure-activity relationships of sarafotoxins: chemical syntheses of chimera peptides of sarafotoxins S6b and S6c08/09/2019
- Cardiac and vascular actions of SARAFOTOXIN S6B (cas 116303-65-2) and endothelin-108/08/2019
- Cardiac output effects of endothelin-1, -2 and -3 and SARAFOTOXIN S6B (cas 116303-65-2) in conscious rats08/07/2019
- Cardiovascular effects of two disulfide analogues of SARAFOTOXIN S6B (cas 116303-65-2)08/06/2019
- 1H NMR Study of the solution structure of sarafotoxin-S6b08/05/2019
- Cerebellar neurons and glia respond differentially to endothelins and SARAFOTOXIN S6B (cas 116303-65-2)08/04/2019
- Atypical receptors mediate the response to endothelin-1 and SARAFOTOXIN S6B (cas 116303-65-2) in the human umbilical artery08/02/2019