sec-Butanol

Molecule structure of sec-Butanol (CAS NO.78-92-2):

IUPAC Name: Butan-2-ol 
Molecular Weight: 74.1216 g/mol
Molecular Formula: C₄H₁₀O 
Density: 0.801 g/cm³ 
Melting Point: −115 °C(lit.)
Boiling Point: 96.6 °C at 760 mmHg 
Flash Point: 26.7 °C
Index of Refraction: 1.393
Molar Refractivity: 22.07 cm³
Molar Volume: 92.4 cm³
Surface Tension: 24.3 dyne/cm 
Enthalpy of Vaporization: 40.75 kJ/mol
Vapour Pressure: 25.2 mmHg at 25 °C 
Storage Temp.: Flammables area
Water Solubility: 12.5 g/100 mL (20 °C)
Sensitive: Hygroscopic 
Stability: Stable. Flammable. Substances to be avoided include acids, acid chlorides, acid anhydrides, oxidizing agents and halogens.
XLogP3: 0.6
H-Bond Donor: 1
H-Bond Acceptor: 1
Rotatable Bond Count: 1
Exact Mass: 74.073165
MonoIsotopic Mass: 74.073165
Topological Polar Surface Area: 20.2
Heavy Atom Count: 5
Canonical SMILES: CCC(C)O
InChI: InChI=1S/C4H10O/c1-3-4(2)5/h4-5H,3H2,1-2H3
InChIKey: BTANRVKWQNVYAZ-UHFFFAOYSA-N
EINECS: 201-158-5
Product Categories: Industrial/Fine Chemicals

 sec-Butanol (CAS NO.78-92-2) is mainly converted to butanone which is an important in industrial solvent and found in many domestic cleaning agents and paint removers. It is also sometimes used as a solvent.

In industry, sec-Butanol is manufactured by the hydration of 1-butene or 2-butene :

Community Right-To-Know List. Reported in EPA TSCA Inventory.

Hazard Codes: Xi
Risk Statements: 10-36/37-67 
R10:Flammable. 
R36/37:Irritating to eyes and respiratory system. 
R67:Vapours may cause drowsiness and dizziness.
Safety Statements: 13-24/25-26-46-7/9 
S13:Keep away from food, drink and animal foodstuffs. 
S24/25:Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S46:If swallowed, seek medical advice immediately and show this container or label. 
S7:Keep container tightly closed. 
S9:Keep container in a well-ventilated place.
RIDADR: UN 1120 3/PG 3
WGK Germany: 1
RTECS: EO1750000
HazardClass: 3
PackingGroup: II
HS Code: 29051490
Poison by intravenous and intraperitoneal routes. Mildly toxic by ingestion. Experimental reproductive effects. A skin and eye irritant. See also n-BUTYL ALCOHOL and ALCOHOLS. Dangerous fire hazard when exposed to heat or flame. Auto-oxidizes to an explosive peroxide. Ignites on contact with chromium trioxide. To fight fire, use water spray, alcohol foam, CO₂, dry chemical. Incompatible with oxidizing materials. When heated to decomposition it emits acrid smoke and fumes.

OSHA PEL: TWA 100 ppm
ACGIH TLV: TWA 100 ppm
DFG MAK: 100 ppm (310 mg/m³)

For occupational chemical analysis use NIOSH: Alcohols II, 1401.

 sec-Butanol (CAS NO.78-92-2) is also named as 1-Methyl propanol ; 1-Methyl-1-propanol ; 1-Methylpropyl alcohol ; 2-01-00-00400 (Beilstein Handbook Reference) ; 2-Butanol (natural) ; 2-Butyl alcohol ; 2-Hydroxybutane ; AI3-24189 ; Alcool butylique secondaire ; Alcool butylique secondaire [French] ; BRN 0773649 ; Butan-2-ol ; Butanol secondaire ; Butanol secondaire [French] ; Butyl alcohol, sec- ; Butylene hydrate ; CCS 301 ; Caswell No. 119C ; Ethyl methyl carbinol ; Ethylmethyl carbinol ; HSDB 674 ; Methyl ethyl carbinol ; Methylethyl carbinol ; Methylethylcarbinol ; NSC 25499 ; s-Butanol ; s-Butyl alcohol ; sec-Butyl alcohol . sec-Butanol (CAS NO.78-92-2) is colourless liquid with an alcohol odor. It is soluble in water. Moderately irritates the eyes and skin. Prolonged and repeated contact may cause defatting and drying of the skin. Vapors may irritate the nose, throat and respiratory tract. May be harmful by ingestion. Acetyl bromide reacts violently with alcohols or water. Mixtures of alcohols with concentrated sulfuric acid and strong hydrogen peroxide can cause explosions. Alkyl hypochlorites are violently explosive. They are readily obtained by reacting hypochlorous acid and alcohols either in aqueous solution or mixed aqueous-carbon tetrachloride solutions. Chlorine plus alcohols would similarly yield alkyl hypochlorites. They decompose in the cold and explode on exposure to sunlight or heat. Tertiary hypochlorites are less unstable than secondary or primary hypochlorites. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence.