spironolactone
(52-01-7)
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Required Fields
Chemistry
MF: C24H32O4S
MW: 416.57
EINECS: 200-133-6
mp : 207-208 °C(lit.)
alpha : -37 o (c=1, CHCl3)
refractive index : -36 ° (C=1, CHCl3)
Water Solubility : practically insoluble
Merck : 8760
Uses
Spironolactone (marketed under the trade names Aldactone, Novo-Spiroton, Aldactazide, Spiractin, Spirotone, Verospiron or Berlactone) is a diuretic and is used as an antiandrogen.
Spironolactone is a synthetic 17-lactone drug that is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat heart failure, ascites in patients with liver disease, low-renin hypertension, hypokalemia and Conn's syndrome.
Safety Profile
Risk Statements : 60-40-36/37/38
Safety Statements : 53-22-36/37/39-45-36-26
Hazard Codes : T,Xn,Xi
WGK Germany : 3
RTECS : TU4725000
