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(1R)-(-)-Menthyl acetate

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Name

(1R)-(-)-Menthyl acetate

EINECS 220-076-0
CAS No. 2623-23-6 Density 0.92 g/cm3
PSA 26.30000 LogP 3.01030
Solubility 23.2mg/L at 20℃ Melting Point <25 °C
Formula C12H22O2 Boiling Point 229.1 °C at 760 mmHg
Molecular Weight 198.305 Flash Point 92.2 °C
Transport Information N/A Appearance N/A
Safety 24/25 Risk Codes N/A
Molecular Structure Molecular Structure of 2623-23-6 ((1R)-(-)-Menthyl acetate) Hazard Symbols N/A
Synonyms

Cyclohexanol,5-methyl-2-(1-methylethyl)-, acetate, (1R,2S,5R)- (9CI);Cyclohexanol,5-methyl-2-(1-methylethyl)-, acetate, [1R-(1a,2b,5a)]-;Menthol, acetate,(1R,3R,4S)-(-)- (8CI);(-)-Menthol acetate;(-)-Menthyl acetate;(-)-p-Menthylacetate;(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexanol acetate;Acetic acid(R)-menthyl ester;L-Menthyl acetate;NSC 3722;NSC 52970;l-(-)-Menthylacetate;l-Menthol acetate;

Article Data 194

(1R)-(-)-Menthyl acetate Chemical Properties

Product Name: (1R)-(-)-Menthyl acetate (2623-23-6)


Molecular Formula: C12H22O2
Molecular Weight: 198.3g/mol
Mol File: 2623-23-6.mol
Einecs: 220-076-0
Appearance: Colorless liquid
Melting Point:
Boiling point: 229-230 °C(lit.)
Flash Point: 92.2 °C
Density: 0.92 g/mL at 25 °C(lit.)
Refractive index: n20/D 1.447(lit.)
Product Categories: Pharmaceutical Raw Materials; Monocyclic Monoterpenes; Biochemistry; Terpenes; Esters; Chiral Building Blocks; EstersAlphabetic; M; MEA - MES; Organic Building Blocks
Synonyms of  (1R)-(-)-Menthyl acetate (2623-23-6): 2-isopropyl-5-methyl-,acetate,l-cyclohexan-1-o ; 5-methyl-2-(1-methylethyl)-,acetate,[1R-(1.alpha.,2.beta.,5.alpha.)]-Cyclohexanol ; acetate,(1r,3r,4s)-(-)-mentho ; aceticacid(1R)-menthylester ; cyclohexanol,5-methyl-2-(1-methylethyl)-,acetate,(1r-(1alpha,2beta,5alpha) ; cyclohexanol,5-methyl-2-(1-methylethyl)-,acetate,[1theta-(1alpha,2beta,5 ; l-p-menth-3-ylacetate;p-menth-3-ylester,l-aceticaci .

(1R)-(-)-Menthyl acetate Uses

GB 2760 - 1996 provides for the use of edible spices. (1R)-(-)-Menthyl acetate (2623-23-6) is mainly used in the preparation of mint, fruit and berries fragrance.

(1R)-(-)-Menthyl acetate Production

By pepper mint oil in the sample derived from a single (l type).
In the presence of anhydrous sodium acetate, acetic anhydride by the menthol and the reaction by washing, distillation derived (dl type).

 

(1R)-(-)-Menthyl acetate Toxicity Data With Reference

Low toxicity by ingestion and skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rabbit LD50 skin > 5gm/kg (5000mg/kg)   Food and Cosmetics Toxicology. Vol. 14, Pg. 477, 1976.
rat LD50 oral > 5gm/kg (5000mg/kg)   Food and Cosmetics Toxicology. Vol. 14, Pg. 477, 1976.

(1R)-(-)-Menthyl acetate Consensus Reports

Reported in EPA TSCA Inventory.

(1R)-(-)-Menthyl acetate Safety Profile

Safety Information of (1R)-(-)-Menthyl acetate (2623-23-6):
Safety Statements: 24/25
24:  Avoid contact with skin 
25:  Avoid contact with eyes 

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