Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

(Z)-Hymenialdisine

Related Products

Hot Products

Name

(Z)-Hymenialdisine

EINECS N/A
CAS No. 82005-12-7 Density 2.2 g/cm3
PSA 112.37000 LogP 0.85980
Solubility Soluble in DMSO. Melting Point 160-164oC
Formula C11H10BrN5O2 Boiling Point N/A
Molecular Weight 324.137 Flash Point N/A
Transport Information N/A Appearance Light Yellow Solid
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 82005-12-7 (10Z-HYMENIALDISINE) Hazard Symbols N/A
Synonyms

Pyrrolo[2,3-c]azepin-8(1H)-one,4-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-,(Z)-;Hymenialdesine;Hymenialdisine;

Article Data 5

(Z)-Hymenialdisine Specification

The (Z)-Hymenialdisine, with the CAS registry number 82005-12-7, is also known as Pyrrolo(2,3-c)azepin-8(1H)-one,4-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-, (4Z)-. It belongs to the product categories of Protein Kinase Inhibitors and Activators; Heterocycles; Tyrosine Kinase Inhibitors. This chemical's molecular formula is C11H10BrN5O2 and molecular weight is 324.13. What's more, it is light yellow solid and it should be kept in a cold and dry place.

Preparation of (Z)-Hymenialdisine: this chemical can be prepared by 4-(2-Amino-3H-imidazol-4-yl)-2,5-dibromo-6,7-dihydro-1H-pyrrolo[2,3-c]azepin-8-one. This reaction needs reagent AcOH at temperature of 120 °C. The reaction time is 48 hours. The yield is 65 %.

(Z)-Hymenialdisine can be prepared by 4-(2-Amino-3H-imidazol-4-yl)-2,5-dibromo-6,7-dihydro-1H-pyrrolo[2,3-c]azepin-8-one

Uses of (Z)-Hymenialdisine: (1) it is used as a potent inhibitor of a variety of kinases including MEK-1, GSK-3, and CKI; (2) it also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations; (3) it is used as a marine sponge alkaloid, a natural product.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 82005-12-7