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1-(3-Methoxypropyl)-4-piperidinamine

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Name

1-(3-Methoxypropyl)-4-piperidinamine

EINECS 431-950-8
CAS No. 179474-79-4 Density 0.946
PSA 38.49000 LogP 1.08420
Solubility N/A Melting Point N/A
Formula C9H20N2O Boiling Point 249℃
Molecular Weight 172.271 Flash Point 105℃
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 179474-79-4 (1-(3-Methoxypropyl)-4-piperidinamine) Hazard Symbols N/A
Synonyms

1-(3-Methoxypropyl)-4-piperidinamine;

Article Data 2

1-(3-Methoxypropyl)-4-piperidinamine Synthetic route

519147-89-8

1-[3-(methyloxy)propyl]-4-piperidinecarboxamide

179474-79-4

4-amino-1-(3-methoxypropyl)piperidine

Conditions
ConditionsYield
With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; potassium hydroxide In water; acetonitrile at 5 - 25℃; for 13h;83%

C22H28N2O

179474-79-4

4-amino-1-(3-methoxypropyl)piperidine

Conditions
ConditionsYield
With hydrogenchloride In water at 0 - 20℃; pH=1 - 2;81%
1249604-45-2

ethyl 1-(3-methoxy-propyl)-piperidin-4-carboxylate

179474-79-4

4-amino-1-(3-methoxypropyl)piperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ammonia / methanol / 60 °C
2: potassium hydroxide; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione / water; acetonitrile / 13 h / 5 - 25 °C
View Scheme

methyl-1-(3-methoxypropyl)piperidine-4-carboxylate

179474-79-4

4-amino-1-(3-methoxypropyl)piperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ammonium hydroxide / 60 °C
2: potassium hydroxide; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione / water; acetonitrile / 13 h / 5 - 25 °C
View Scheme
13035-19-3

4-aminopiperidine

179474-79-4

4-amino-1-(3-methoxypropyl)piperidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: boron trifluoride diethyl etherate / toluene / Reflux
2.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
2.2: 3 h / 20 °C
3.1: hydrogenchloride / water / 0 - 20 °C / pH 1 - 2
View Scheme
179474-79-4

4-amino-1-(3-methoxypropyl)piperidine

110-15-6

succinic acid

123654-26-2

4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-carboxylic acid

prucalopride succinic acid

Conditions
ConditionsYield
Stage #1: 4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-carboxylic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran for 1.5h;
Stage #2: 4-amino-1-(3-methoxypropyl)piperidine In tetrahydrofuran at 45℃; for 4h;
Stage #3: succinic acid In ethanol at 20℃; for 2h; Solvent; Reagent/catalyst; Temperature;
94%
179474-79-4

4-amino-1-(3-methoxypropyl)piperidine

123654-26-2

4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-carboxylic acid

179474-81-8

prucalopride

Conditions
ConditionsYield
Stage #1: 4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-carboxylic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran for 0.416667h;
Stage #2: 4-amino-1-(3-methoxypropyl)piperidine In tetrahydrofuran at 45 - 50℃; for 4h;
85%
179474-79-4

4-amino-1-(3-methoxypropyl)piperidine

8-chloro-3-methyl-1,7-naphthyridin-2(1H)-one

C18H26N4O2

Conditions
ConditionsYield
With Caddick catalyst In 2-methyltetrahydrofuran at 20 - 140℃; for 0.5h; Microwave irradiation;19%
179474-79-4

4-amino-1-(3-methoxypropyl)piperidine

519147-79-6

5-AMINO-6-CHLORO-2-METHYL-N-{1-[3-(METHOXY)PROPYL]-4-PIPERIDINYL}IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE

519147-96-7

5-amino-6-chloro-2-ethylimidazo[1,2-a]pyridine-8-carboxylic acid

179474-79-4

4-amino-1-(3-methoxypropyl)piperidine

519148-35-7

5-AMINO-6-CHLORO-2-ETHYL-N-{1-[3-(METHOXY)PROPYL]-4-PIPERIDINYL}IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE

Conditions
ConditionsYield
In 5-Amino-N-[(1-butyl-4-piperidinyl)methyl]-6-chloro-2-methylimidazo

1-(3-Methoxypropyl)-4-piperidinamine Chemical Properties

Following is the structure of 4-Piperidinamine,1-(3-methoxypropyl)- (CAS NO.179474-79-4):
                         
Empirical Formula: C9H20N2O

1-(3-Methoxypropyl)-4-piperidinamine Specification

 4-Piperidinamine,1-(3-methoxypropyl)- , its cas register number 179474-79-4. It also can be called 1-(3-Methoxypropyl)-4-piperidinamine .

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