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1,2-Dibromopropane

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1,2-Dibromopropane

EINECS 201-139-1
CAS No. 78-75-1 Density 1.926 g/cm3
PSA 0.00000 LogP 2.16470
Solubility slightly soluble in water Melting Point -55 °C
Formula C3H6Br2 Boiling Point 140.4 °C at 760 mmHg
Molecular Weight 201.889 Flash Point 21.9 °C
Transport Information UN 1993 3/PG 3 Appearance Colorless liquid
Safety 23-24/25-36/37/39-26-16 Risk Codes 10-20/22-36/37/38-20/21/22
Molecular Structure Molecular Structure of 78-75-1 (1,2-Dibromopropane) Hazard Symbols HarmfulXn
Synonyms

2,3-Dibromopropane;Propylene dibromide;

Article Data 93

1,2-Dibromopropane Chemical Properties

Molecular Formula: C3H6Br2
Formula Weight: 201.89
IUPAC Name: 1,2-Dibromopropane
Synonyms: 1,2-Propylenebromide ; 2-Bromopropylbromide ; (RS)-Dibrompropan ; Propane,1,2-dibromo- ; 1,2-Propylene Dibromide
Melting Point: -55 °C
Boiling Point: 140-142 °C(lit.)
Density of 2,3-Dibromopropane (78-75-1): 1.937 g/mL at 25 °C(lit.)
Refractive index : n20/D 1.519(lit.)
Flash Point: 35 °
Storage temp.: Flammables area
Water Solubility: 2,3-Dibromopropane (78-75-1) is slightly soluble
Chemical Properties: 2,3-Dibromopropane (78-75-1) is a colorless liquid.
Stability: 2,3-Dibromopropane (78-75-1) is stable. Flammable. Incompatible with strong oxidizing agents, strong bases, magnesium.

1,2-Dibromopropane Uses

 2,3-Dibromopropane (78-75-1) is used as an intermediate, raw material, chemical reagent and solvent in organic synthesis.

1,2-Dibromopropane Production

1. 2,3-Dibromopropane (78-75-1) is formed from propylene by direct bromination.
2. It is derived from bromopropane by bromination.
3. Propanol bromide method

1,2-Dibromopropane Toxicity Data With Reference

1.    

sln-dmg-orl 5 mmol/L

    EXPEAM    Experientia. 30 (1974),621.
2.    

orl-rat LD50:741 mg/kg

    GISAAA    Gigiena i Sanitariya. 41 (3)(1976),105.
3.    

ihl-rat LC50:12 g/m3/4H

    85GMAT    Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,43.
4.    

orl-mus LD50:676 mg/kg

    GISAAA    Gigiena i Sanitariya. 41 (3)(1976),105.
5.    

ipr-mus LD50:75 mg/kg

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD691-490 .

1,2-Dibromopropane Consensus Reports

Reported in EPA TSCA Inventory.

1,2-Dibromopropane Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of Br. See also PROPANE and BROMIDES.
Safety: DANGER: FLAMMABLE, irritates skin, eyes, lungs
Hazard Codes : Xn: Harmful
Risk Statements : 10: Flammable
20/22: Harmful by inhalation and if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
Safety Statements : 23: Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer)
24/25: Avoid contact with skin and eyes
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
16: Keep away from sources of ignition - No smoking 
RIDADR : UN 1993 3/PG 3
WGK Germany : 3
RTECS : TX8574000
HazardClass : 3
PackingGroup : III
HS Code : 29033036

1,2-Dibromopropane Standards and Recommendations

ASSAY: 98.0% MIN
WATER: 0.1% max

1,2-Dibromopropane Specification

 2,3-Dibromopropane (78-75-1) is a colorless liquid slightly soluble in water (miscible with organic solvents). It is stable under ordinary conditions and mainly used as a intermediate for the synthesis of pharmaceuticals and other organic compounds. 2,3-Dibromopropane (78-75-1) is considered non-flammable.

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